Postdoctoral Associate

Duke Careers • Durham, NC

7d • Onsite

About The Position

The Duke University laboratory of Dorothy Sipkins, M.D., Ph.D. is seeking a highly motivated postdoctoral associate with research interest in metastasis and the tumor microenvironment. Our group has a diverse and stimulating environment with projects in basic and translational research as well as clinical trial studies. Duke University is an exceptional environment for research because of its rich intellectual community and pervasive spirit of collegiality. The resources and support for postdoctoral fellows at Duke are outstanding, with numerous professional development workshops and training opportunities. The Sipkins Lab is within the Division of Hematologic Malignancies and Cellular Therapy, a division of the Department of Medicine and part of the Duke Cancer Institute (DCI). The DCI is a single entity that integrates and aligns research and patient care with the goals of decreasing the burden of cancer and accelerating scientific progress.

Requirements

• PhD in cell biology, immunology, or other relevant areas of biomedical sciences.
• Willingness to work with animal models is a must.
• Motivated, innovative, with strong problem-solving and interpersonal skills and excitement to learn new techniques.

Nice To Haves

• Experience in in vivo mouse models.
• Experience in Immunology (flow cytometry).
• Experience in Molecular biology techniques.

Responsibilities

• Dissect the key signaling events that regulate tumor cell peripheral nerve invasion (PNI) in pancreatic cancer.
• Study the role of integrin alpha-6:laminin and neurotrophin cell signaling interactions in this process.
• Test the efficacy of integrin alpha-6 blockade to prevent PNI and reduce tumor progression in pancreatic cancer.
• Analyze primary patient correlative research samples for expression of relevant signaling molecules and their association with PNI and pancreatic cancer disease progression.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Ph.D. or professional degree