POSTDOCTORAL ASSOCIATE - Arnab Chatterjee Lab - Chemistry
About The Position
Calibr-Skaggs Institute for Innovative Medicines, a division of Scripps Research, is seeking a Postdoctoral Associate to join its medicinal chemistry group and contribute to early-stage translational research. The postdoctoral researcher will work with an interdisciplinary team to synthesize and characterize small molecules representing potential new therapeutic approaches to unmet medical needs. The work includes designing and synthesizing analogs to optimize potency, pharmacokinetics, safety, and in vivo efficacy of potential drug candidates. Research findings will be published in high-impact, peer-reviewed journals. Postdoctoral Associate appointments are intended to develop scholarly competence and are conducted under the supervision of a Scripps Research faculty member. Appointments are normally not renewed beyond five total years. Associates may not apply for external funding as a Principal Investigator or Co-Principal Investigator without prior approval from a Departmental Chair, and they do not have consulting privileges. The position is based on site at the La Jolla campus.
Requirements
- Ph.D. in chemistry or an equivalent degree from a recognized institution of higher learning; a pending doctoral degree may be considered with approval from the Principal Investigator and Human Resources.
- Strong skills and a proven track record in synthetic organic chemistry, compound purification, and structural characterization.
- Strong literature-search skills and the ability to design and improve synthetic routes for SAR studies and deliver compounds at large scale in a timely manner.
- High motivation and creativity, with the ability to maintain excellent documentation of work.
- Ability to collaborate proficiently and communicate effectively with colleagues and the management team.
- Excellent verbal, written, interpersonal, and collaborative communication skills.
Responsibilities
- Conduct structure-activity relationship (SAR) studies to optimize compounds.
- Design lead-compound analogs using computer-aided molecular modeling, literature research, and medicinal chemistry principles.
- Synthesize and analyze target molecules using techniques such as organic synthesis, column chromatography, HPLC, NMR, and MS/IR/UV spectroscopy.
- Generate candidates with drug-like properties for progression to clinical studies.
Benefits
- Employer-contributed retirement plan, subject to eligibility, with no required employee contribution.
- Option to contribute to a 403(b) plan.
- Medical, dental, vision, life insurance, disability, and Employee Assistance Program plans.
- Flexible Spending Accounts for medical and dependent care.
- Competitive vacation and sick leave policies.
- Free on-site parking.
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What This Job Offers
Job Type
Full-time
Career Level
Entry Level
Education Level
Ph.D. or professional degree
