PostDoc Fellow - NIH DARPA Chou Lab

Children's Hospital of Philadelphia•Philadelphia, PA
•$20,800 - $110,400

About The Position

The PostDoc Fellow works under the direction and guidance of a principal investigator, assumes responsibility for an ongoing research project, and conducts independent scholarly research contributing to the goals of the project and research group. The role supports professional and career development and helps the fellow broaden their scientific background and acquire new research capabilities. The position is in Dr. Stella Chou’s laboratory in the Hematology Research Division. The laboratory studies pediatric blood diseases, normal and pathologic hematopoietic development, and in vitro generation of red blood cells from induced pluripotent stem cells (iPSCs) for transfusion medicine. Research areas include improving iPSC-derived red blood cell generation and maturation; developing red cell reagents from customized pluripotent stem cells with rare blood cell phenotypes; expanding stem-cell-derived hematopoietic progenitors; applying next-generation sequencing to improve red cell matching and prevent alloimmunization in patients with sickle cell disease; and using CRISPR/Cas9 to manipulate genes relevant to red blood cell proliferation, maturation, and enucleation. The fellow participates in project planning, records and evaluates data, communicates results, develops technical and laboratory-management skills, and gains experience in manuscript and grant writing. The fellow also participates in seminars, lectures, poster sessions, and presentations at national meetings. The role may include supervising junior laboratory members, developing research methods and protocols, and assisting with other laboratory research projects.

Requirements

  • Doctorate required; the description specifies a terminal degree such as PhD, MD, or DVM.
  • General molecular biology background.
  • Tissue culture experience.
  • Ability to wear a respirator device.

Nice To Haves

  • Background in hematopoiesis.
  • Experience with CRISPR technology.
  • Experience with human primary cell, embryonic stem cell (ESC), or induced pluripotent stem cell (iPSC) culture.

Responsibilities

  • Conduct independent scholarly research and develop new methods and protocols.
  • Participate in project planning and record, interpret, and evaluate data.
  • Communicate research results.
  • Acquire technical, laboratory-management, manuscript-writing, and grant-writing skills.
  • Participate in seminars, lectures, poster sessions, and presentations at national meetings.
  • Supervise junior laboratory members.
  • Assist with other research projects in the laboratory.

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What This Job Offers

Job Type

Full-time

Career Level

Senior

Education Level

Ph.D. or professional degree

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