Post Doctoral Scholar - Comprehensive Cancer Center

The Ohio State University

1d • Onsite

About The Position

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC–James) is a nationally recognized, NCI-designated comprehensive cancer center integrated within one of the nation’s largest public research universities. The OSUCCC–James brings together world-class researchers and clinicians to accelerate discoveries and translate them into improved cancer prevention, detection, and treatment. The Thege Laboratory, within the Division of Surgical Oncology, is seeking a highly motivated and creative Postdoctoral Scholar to join our team. Our research is focused on developing rational drug combinations for KRAS-mutant pancreatic and lung cancers, with an emphasis on identifying therapeutic vulnerabilities and overcoming resistance mechanisms.

Requirements

• PhD in Cancer Biology, Molecular Biology, Biomedical Sciences, or a related field
• Strong background in molecular and cellular biology techniques, including cell culture, nucleic acid handling, and protein analysis
• Demonstrated experience with animal models (mouse experiments required)
• Hands-on expertise in wet lab research, with the ability to work independently

Nice To Haves

• Experience with organoid culture systems or primary patient-derived samples
• Familiarity with functional genomics approaches, including CRISPR-based screening
• Experience analyzing or interpreting omics datasets (RNA-seq, single-cell, or spatial data)
• Basic proficiency in coding or bioinformatics (e.g., R, Python) is strongly preferred
• Prior experience working in cancer biology, particularly in pancreatic, lung, or KRAS-driven cancers, is a plus.

Responsibilities

• Design, execute, and interpret independent and collaborative research projects aligned with lab goals
• Perform in vitro and in vivo experiments, including drug screening and mouse studies
• Develop and optimize organoid and tumor models
• Conduct and/or analyze high-throughput sequencing datasets (scRNA-seq, spatial transcriptomics, bulk RNA-seq)
• Maintain detailed experimental records and ensure rigorous reproducibility
• Prepare manuscripts and contribute to grant applications
• Present findings at lab meetings, institutional seminars, and national/international conferences
• Collaborate effectively with multidisciplinary teams across the OSUCCC

Benefits

• Medical, dental and vision coverage, with Ohio State paying a significant portion of the cost.
• Paid time off, including sick and vacation time and 11 holidays.
• State retirement plan or an alternative retirement plan, both with generous employer contributions.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Ph.D. or professional degree