Portfolio Leader (Cross Portfolio + Strategy & Operations)

Genentech•Daly City, CA
•$167,800 - $311,600

About The Position

At Roche/Genentech, the Portfolio Leader supports the ambition to deliver 20 transformative medicines addressing diseases with the highest societal burden by 2030. The role serves as a strategic partner and operational leader, helping shape and deliver a transformative Pharma portfolio. It partners with the Head of PSM to drive strategy, business planning, operations, and team culture so the PSM team is aligned, agile, and positioned to have impact in a complex and evolving landscape. The role also leads and contributes to cross-portfolio initiatives, partnering with senior Pharma leaders and cross-functional teams to shape portfolio strategy, assess portfolio dynamics, and develop insights and strategic options for portfolio-wide decisions and prioritization. The balance between PSM-focused strategy and operations and broader portfolio work may shift over time according to business needs. Responsibilities include translating PSM’s strategic vision into actionable priorities; architecting and stewarding the PSM ecosystem; facilitating leadership and all-staff meetings; developing processes to deploy talent against high-impact needs; operationalizing priorities and building team culture; representing PSM on Product Development workstreams; and maintaining portfolio networks across gRED, pRED, and GPS. The Portfolio Leader also structures ambiguous cross-portfolio questions, synthesizes analyses and stakeholder perspectives into recommendations, assesses portfolio risk, value, mix, competitive positioning, and performance, and supports decision-makers in evaluating strategic options, investment trade-offs, and prioritization approaches.

Requirements

  • Bachelor’s degree required.
  • Minimum 10 years of experience in operations, strategy, and/or R&D within the biopharma industry.
  • Experience in strategy development and linking strategy to tactics.
  • Structured problem-solving and strategic-thinking skills, including framing ambiguous questions, synthesizing information, and developing clear, practical recommendations.
  • Strong organizational and project-management skills, including setting priorities, managing milestones and dependencies, and delivering special projects.
  • Strong understanding of the drug-development lifecycle.
  • Experience in cross-portfolio strategy or portfolio management, including assessing portfolio dynamics, strategic options, and prioritization trade-offs.
  • Strong analytical acumen, including interpreting portfolio-level risk/value assessments, business cases, metrics, and benchmarks and turning them into actionable recommendations.
  • Demonstrated experience as a strategic thought partner to senior leaders and teams, with a track record of driving change and innovation.
  • Extensive strategic planning, stakeholder-management, and operational-execution expertise, including leading multiple complex, cross-functional initiatives.

Nice To Haves

  • MBA or advanced degree in science, business, or a related field.

Responsibilities

  • Partner with the Head of PSM and PSM Leadership Team to realize PSM’s strategic vision and translate it into actionable priorities.
  • Partner with Leadership Team members to co-create and implement PSM-wide initiatives.
  • Architect and steward the PSM ecosystem, integrating culture, communications, and operational frameworks.
  • Plan and facilitate PSM Leadership Team and All Staff meetings using agile practices to support rigorous discussion, clear decisions, and actionable outcomes.
  • Monitor team performance and organizational health and identify opportunities to strengthen the PSM ecosystem.
  • Build and manage systems and processes to match team skills and interests to high-impact business needs and PSM priorities.
  • Operationalize strategic priorities and champion a team culture of learning, adaptability, operational excellence, and fun.
  • Represent PSM on Product Development workstreams as needed.
  • Maintain a strong Portfolio network with peer groups in gRED, pRED, and GPS.
  • Partner with senior Pharma leaders and teams to shape portfolio-wide strategy and lead cross-portfolio initiatives and special projects.
  • Structure complex, ambiguous questions; define necessary work and analysis; synthesize evidence and stakeholder perspectives into recommendations; and align contributors on plans and milestones.
  • Assess and communicate portfolio risk, value, mix, competitive positioning, and performance to inform strategy and prioritization.
  • Synthesize quantitative and qualitative analyses, external benchmarking, and business-planning inputs into executive-ready insights and recommendations.
  • Partner with decision-makers to frame portfolio-level choices, assess strategic options and investment trade-offs, and use valuation inputs, business cases, and risk assessments where relevant.
  • Help shape decision pathways and prioritization approaches that support timely, high-quality portfolio decisions.

Benefits

  • A discretionary annual bonus may be available based on individual and Company performance.
  • The position qualifies for company benefits detailed at the provided link; specific benefits are not listed in the posting.
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