Portfolio Leader (Cross Portfolio + Strategy & Operations)

Roche•South San Francisco, CA
•$167,800 - $311,600

About The Position

The Portfolio Leader serves as a strategic partner and operational leader, working with the Head of PSM to drive strategy, business planning, operations, and team culture. The role helps align and position the PSM team to deliver impact in a complex and evolving landscape. It also involves leading cross-portfolio initiatives and partnering with senior Pharma leaders and cross-functional teams to shape portfolio strategy, assess portfolio dynamics, and develop insights and strategic options for portfolio-wide decisions and prioritization. The balance between PSM-focused strategy and operations and broader portfolio work may change based on business needs. The role stewards the PSM ecosystem, integrating culture, communications, and operational frameworks; facilitates leadership and all-staff meetings; and monitors team performance and organizational health. It builds systems to match team skills and interests to high-impact business needs, operationalizes strategic priorities, and promotes a connected culture of learning, adaptability, operational excellence, and fun. The Portfolio Leader also represents PSM on Product Development workstreams as needed and maintains portfolio networks with peer groups in gRED, pRED, and GPS. For cross-portfolio work, the role structures complex questions, defines needed analysis, synthesizes evidence and stakeholder perspectives into recommendations, and aligns contributors on plans and milestones. It assesses portfolio risk, value, mix, competitive positioning, and performance; frames portfolio choices and investment trade-offs; and helps shape decision pathways and prioritization approaches. The position is based in California for salary-range purposes. Relocation benefits are not available.

Requirements

  • Bachelor’s degree required.
  • At least 10 years of experience in operations, strategy, and/or R&D within the biopharma industry.
  • Experience in strategy development and linking strategy to tactics.
  • Structured problem-solving and strategic-thinking skills, including the ability to frame ambiguous questions, synthesize information, and develop practical recommendations.
  • Strong organizational and project-management skills, including prioritizing, managing milestones and dependencies, and delivering special projects.
  • Strong understanding of the drug-development lifecycle.
  • Experience in cross-portfolio strategy or portfolio management, including assessing portfolio dynamics, strategic options, and prioritization trade-offs.
  • Strong analytical acumen, including the ability to interpret portfolio-level risk/value assessments, business cases, metrics, and benchmarks and turn them into actionable recommendations.
  • Demonstrated experience as a strategic thought partner to senior leaders and teams, with a track record of driving change and innovation.
  • Extensive strategic planning, stakeholder-management, and operational-execution expertise, including leading multiple complex, cross-functional initiatives.

Nice To Haves

  • MBA or advanced degree in science, business, or a related field.

Responsibilities

  • Partner with the Head of PSM and PSM Leadership Team to realize PSM’s strategic vision and translate it into actionable priorities.
  • Partner with Leadership Team members to co-create and implement PSM-wide initiatives.
  • Architect and steward the PSM ecosystem, integrating culture, communications, and operational frameworks.
  • Plan and facilitate PSM Leadership Team and All Staff meetings using agile practices to support discussion, decision-making, and actionable outcomes.
  • Monitor team performance and organizational health and identify opportunities to strengthen the PSM ecosystem.
  • Build and manage systems and processes that match team skills and interests to high-impact business needs and PSM priorities.
  • Operationalize strategic priorities and foster a connected team culture of learning, adaptability, operational excellence, and fun.
  • Represent PSM on Product Development workstreams as needed and maintain a strong portfolio network with peer groups in gRED, pRED, and GPS.
  • Partner with senior Pharma leaders and teams to shape portfolio-wide strategy and lead cross-portfolio initiatives and special projects.
  • Structure complex and ambiguous questions, define the work and analysis required, synthesize evidence and stakeholder perspectives into recommendations, and align contributors on plans and milestones.
  • Assess and communicate portfolio risk, value, mix, competitive positioning, and performance to inform portfolio strategy and prioritization.
  • Synthesize quantitative and qualitative analyses, external benchmarking, and business-planning inputs into executive-ready insights and recommendations.
  • Partner with decision-makers to frame portfolio choices, assess strategic options and investment trade-offs, and use valuation inputs, business cases, and risk assessments where relevant.
  • Help shape fit-for-purpose decision pathways and prioritization approaches for timely, high-quality portfolio decisions.

Benefits

  • A discretionary annual bonus may be available based on individual and Company performance.
  • The position qualifies for company benefits detailed at the link referenced in the posting; specific benefits are not listed.
  • Relocation benefits are not available.
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