2027 Summer OTD Chemistry Summer Internship – Undergraduate

AstraZeneca•Cambridge, MA
•$37 - $39•Onsite

About The Position

Join AstraZeneca's Oncology Targeted Discovery (OTD) Chemistry team in Kendall Square, Cambridge, Massachusetts, for a hands-on summer internship within Oncology Research & Development. As an OTD Chemistry Intern, you will contribute to a specialized short-term project supporting capability building and key business initiatives, working alongside experienced scientists designing and developing novel molecules for oncology drug discovery. Applicants select one of three specialties: Synthetic Organic / Medicinal Chemistry (wet lab), focused on synthesizing and purifying novel molecules and characterizing them with analytical techniques; Analytical / Structure Chemistry (wet lab), embedded with the Separation Sciences team to learn chiral and achiral purification using SFC and HPLC instruments; or Computational Chemistry (dry lab, office-based), using computational and data analysis tools to design, evaluate, and triage molecule design ideas. The position is on site in Cambridge, MA, five days a week. Relocation assistance and OPT support are not provided. The hourly pay range is $37–$39. The internship is intended for undergraduate rising juniors graduating in 2029 or rising seniors graduating in 2028. Applications were posted October 27, 2026, and close November 12, 2026.

Requirements

  • Currently enrolled as an undergraduate rising junior graduating in 2029 or rising senior graduating in 2028.
  • Pursuing a degree in Chemistry or Biochemistry; Chemistry is preferred.
  • Completion of Organic Chemistry I and II lecture courses and accompanying Organic Chemistry Laboratory coursework.
  • US work authorization at the time of application that does not require future sponsorship; OPT support will not be provided.
  • Ability to report on site in Cambridge, MA five days a week.

Nice To Haves

  • Previous undergraduate research experience in synthetic organic chemistry, analytical chemistry, or computational chemistry is strongly preferred.
  • For strong applicants without previous undergraduate research experience, completion of an advanced organic or analytical chemistry laboratory course is beneficial.

Responsibilities

  • Contribute to a specialized short-term project supporting capability building and key business initiatives.
  • Work alongside experienced scientists designing and developing novel molecules for oncology drug discovery.
  • Depending on the selected specialty, synthesize and purify molecules and characterize them using analytical techniques; learn chiral and achiral purification using SFC and HPLC; or use computational and data analysis tools to design, evaluate, and triage molecule design ideas.
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