Givaudan Careers Medicinal Chemist - Taste Modulation

Givaudan•Cincinnati, OH

9d•Onsite

About The Position

Givaudan is seeking a Medicinal Chemist to join their innovative and multidisciplinary team in Cincinnati, Ohio. This hands-on laboratory role focuses on the design, synthesis, purification, and characterization of small molecules, peptides, and related compounds to support discovery programs, particularly in taste modulation. The position requires collaboration with internal and external specialists in cheminformatics, molecular biology, analytical chemistry, and applications. The successful candidate will contribute to efficient compound design, interpret SAR data, support hit-to-lead and lead optimization programs, and ensure compliance with safety and environmental regulations. This role also involves contributing to patent filings, assessing the IP landscape, and supporting scale-up activities with CRO partners.

Requirements

Master of Science or higher education in Organic Chemistry or Medicinal Chemistry required
4+ years of industrial experience in medicinal, organic, or discovery chemistry
Familiarity with medicinal chemistry concepts and SAR-driven optimization
Familiarity with computational chemistry or molecular modeling tools
Hands-on expertise in synthetic organic chemistry and modern purification methods
Practical experience with compound characterization techniques, including NMR and mass spectrometry

Nice To Haves

Preferred experience in pharmaceutical industry or other where experience is working with biologists and computational chemists to design new drugs or ligands.

Responsibilities

Independently design, synthesize, and characterize taste active molecules with suitable toxicology and regulatory profiles.
Interpret structure–activity relationship (SAR) data and contribute to compound design strategies.
Support hit to lead and lead optimization programs.
Work in collaboration with biology, analytical, computational chemistry, and application teams.
Troubleshoot synthetic challenges and develop practical, efficient synthetic solutions.
Ensure laboratory work is conducted in compliance with safety, health, and environmental regulations, consulting with these teams.
Contribute to patent filings and assessment of competitor IP landscape.
Maintain a high level of modern medicinal chemistry/drug discovery knowledge, skills and best practices.
Participate in project/planning discussions and concisely present results/plans in project team meetings.
Support scale-up activities and coordinate with external CRO partners.