Medical Director: Gastroenterology, Pulmonary, Rheumatology, Nephrology

Genentech • Daly City, CA

7d • $213,400 - $396,200 • Hybrid

About The Position

We advance science so that we all have more time with the people we love. The Early Clinical Development (ECD) OMNI group at Genentech drives innovation across a broad portfolio of immunology indications, advancing breakthrough science from First-in-Human studies through Proof-of-Concept and initial pivotal decisions. Driven by gRED’s mission to make fundamental scientific discoveries and help develop them into best-in-class therapeutics that provide unique benefits to patients, our team translates complex biology into transformative therapies.

Requirements

• M.D. with Board Certification or eligibility in Gastroenterology, Pulmonary, Rheumatology, Nephrology, or a related specialty (M.D./Ph.D. preferred).
• 2+ years of clinical, translational, or basic research experience within academia or the biopharmaceutical industry, with a demonstrated focus on immunology or inflammation.
• Thorough understanding of early clinical drug development principles (Phases I–II), trial methodology, GCP/ICH guidelines, and sophisticated clinical data interpretation.
• Adept at synthesizing complex biomarker and safety data to shape asset strategy and influence decisions across cross-functional matrix teams.
• Highly effective communicator capable of building strong collaborative networks with academic investigators, regulatory bodies, and internal research partners.

Responsibilities

• Author clinical protocols and design early-phase (Phase I/II) studies to establish biologic and clinical proof-of-concept for novel molecular entities (NMEs).
• Provide medical oversight, safety monitoring, and clinical expertise across active trials while collaborating with trial sites, investigators, and CROs.
• Represent Clinical Science on multi-disciplinary Clinical Science Teams (CST) and Protocol Execution Teams (PET), integrating insights across biomarkers, safety, regulatory, and commercial functions.
• Author clinical sections for INDs, IBs, and health authority briefing materials, supporting direct interactions with global regulatory bodies (FDA, EMA).
• Collaborate with internal research groups, external Key Opinion Leaders (KOLs), and scientific advisory boards to refine disease area strategies and inform portfolio decisions.

Benefits

• Relocation benefits are available for this posting.
• A discretionary annual bonus may be available based on individual and Company performance.
• This position also qualifies for the benefits detailed at the link provided below.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Ph.D. or professional degree