Manager / Senior Manager, Program Management – Clinical Operations

Artiva Biotherapeutics•San Diego, CA

3d•Onsite

About The Position

Artiva is seeking a Manager/Sr. Manager, Program Management to support the execution of clinical-stage programs, including randomized controlled trials (RCTs) and ongoing Phase 2 studies. This role will partner closely with Clinical Operations, Clinical Development, Data Management, and external vendors to ensure trials are executed efficiently, on time, and with high quality. This individual will focus on driving operational rigor, maintaining cross-functional alignment, and ensuring clear visibility into timelines, risks, and performance across clinical programs.

Requirements

Bachelor’s degree in life sciences or related field
5–8+ years of experience of program management in biotechnology, pharmaceutical, or clinical research settings
Proven experience supporting or managing clinical trials (Phase 2 and/or Phase 3 preferred)
Solid understanding of clinical trial operations, including site activation, patient enrollment, and vendor management
Strong organizational and project management skills
Ability to manage competing priorities and other tasks as needed
Strong execution and organizational skills
Ability to manage multiple priorities in a fast-paced environment
Effective cross-functional communication and collaboration
Attention to detail with the ability to see the bigger picture
Proactive, solutions-oriented mindset

Nice To Haves

Experience working with CROs and external vendors
Familiarity with clinical systems (e.g., CTMS, EDC)
Exposure to randomized controlled trials (RCTs)
PMP or similar certification (a plus, not required)

Responsibilities

Support end-to-end program management of clinical trials, including RCT startup, enrollment, execution, and closeout activities
Develop and maintain integrated clinical timelines, aligned with key milestones and deliverables
Track progress across sites, vendors, and internal teams to ensure timely execution
Partner with Clinical Operations, Clinical Development, Biostatistics, Data Management, and Regulatory to ensure alignment across all aspects of trial execution
Coordinate inputs and dependencies across functions to maintain program continuity
Support communication across internal teams and external stakeholders
Assist in oversight of CROs and other vendors to ensure deliverables are met on time and within scope
Track vendor performance against timelines, budgets, and quality expectations
Escalate issues and support resolution in collaboration with Clinical Operations
Identify and track risks related to site activation, enrollment, protocol adherence, and data delivery
Support development and execution of mitigation strategies
Ensure timely escalation of critical issues impacting study timelines or quality
Develop and maintain dashboards to track enrollment, site activation, data flow, and key study metrics
Prepare clear, concise program updates for cross-functional teams and leadership
Ensure consistent reporting across ongoing clinical studies
Support clinical governance meetings, including agenda setting, materials preparation, and follow-ups
Ensure decisions, actions, and dependencies are clearly documented and tracked
Drive accountability across teams for agreed-upon deliverables