Manager / Senior Manager, Program Management – Clinical Operations

Artiva Biotherapeutics • San Diego, CA

4d • Onsite

About The Position

Artiva is seeking a Manager/Sr. Manager, Program Management to support the execution of clinical-stage programs, including randomized controlled trials (RCTs) and ongoing Phase 2 studies. This role will partner closely with Clinical Operations, Clinical Development, Data Management, and external vendors to ensure trials are executed efficiently, on time, and with high quality. This individual will focus on driving operational rigor, maintaining cross-functional alignment, and ensuring clear visibility into timelines, risks, and performance across clinical programs.

Requirements

• Bachelor’s degree in life sciences or related field
• 5–8+ years of experience of program management in biotechnology, pharmaceutical, or clinical research settings
• Proven experience supporting or managing clinical trials (Phase 2 and/or Phase 3 preferred)
• Solid understanding of clinical trial operations, including site activation, patient enrollment, and vendor management
• Strong organizational and project management skills
• Ability to manage competing priorities and other tasks as needed
• Strong execution and organizational skills
• Ability to manage multiple priorities in a fast-paced environment
• Effective cross-functional communication and collaboration
• Attention to detail with the ability to see the bigger picture
• Proactive, solutions-oriented mindset

Nice To Haves

• Experience working with CROs and external vendors
• Familiarity with clinical systems (e.g., CTMS, EDC)
• Exposure to randomized controlled trials (RCTs)
• PMP or similar certification (a plus, not required)

Responsibilities

• Support end-to-end program management of clinical trials, including RCT startup, enrollment, execution, and closeout activities
• Develop and maintain integrated clinical timelines, aligned with key milestones and deliverables
• Track progress across sites, vendors, and internal teams to ensure timely execution
• Partner with Clinical Operations, Clinical Development, Biostatistics, Data Management, and Regulatory to ensure alignment across all aspects of trial execution
• Coordinate inputs and dependencies across functions to maintain program continuity
• Support communication across internal teams and external stakeholders
• Assist in oversight of CROs and other vendors to ensure deliverables are met on time and within scope
• Track vendor performance against timelines, budgets, and quality expectations
• Escalate issues and support resolution in collaboration with Clinical Operations
• Identify and track risks related to site activation, enrollment, protocol adherence, and data delivery
• Support development and execution of mitigation strategies
• Ensure timely escalation of critical issues impacting study timelines or quality
• Develop and maintain dashboards to track enrollment, site activation, data flow, and key study metrics
• Prepare clear, concise program updates for cross-functional teams and leadership
• Ensure consistent reporting across ongoing clinical studies
• Support clinical governance meetings, including agenda setting, materials preparation, and follow-ups
• Ensure decisions, actions, and dependencies are clearly documented and tracked
• Drive accountability across teams for agreed-upon deliverables

Benefits

• Medical, Dental, and Vision
• Group Life Insurance
• Long Term Disability (LTD)
• 401(k) Retirement Plan
• Employee Assistance Program (EAP)
• Flexible Spending Account (FSA)
• Paid Time Off (PTO)
• Company paid holidays, including the year-end holiday week
• Bonus.ly recognition program

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level