Lipid Nanoparticle & mRNA Synthesis Intern - Marlborough, MA

Sartorius Stedim • Marlborough, MA

12d • Onsite

About The Position

Sartorius is a leading technology provider to the life sciences and biopharma industries, actively shaping dynamic, innovative, and high growth markets to support better health for more people. To drive the creation of new solutions, Sartorius has formed a global Corporate Research initiative that identifies emerging trends and rapidly translates them into next generation technology solutions. As part of our team in Marlborough, we are seeking a highly motivated intern with a multidisciplinary background in biomedical and bioengineering. As a Research Intern (Lipid Nanoparticle & mRNA Synthesis), you will contribute to the full product development cycle-from concept to prototype-and collaborate closely with engineers and scientists in a multidisciplinary environment. Onsite role based at our Marlborough, MA site

Requirements

• Current graduate student in biomedical, chemical, mechanical engineering, or related field with formal education and experience with lipid nanoparticles and/or nucleic acids.
• Hands-on laboratory experience with RNA synthesis, preferably including in vitro transcription.
• Experience with LNP formulation and characterization, including techniques such as dynamic light scattering (DLS), nanoparticle tracking analysis (NTA), RiboGreen assay, HPLC, chromatography, capillary electrophoresis, ELISA, or related assays.
• Strong oral and written communication skills, with the ability to summarize results and present findings clearly.

Nice To Haves

• Ideal to have an experience with one or more of the following: dynamic light scattering (DLS), nanoparticle tracking analysis, RiboGreen assay, HPLC, chromatography, capillary electrophoresis, ELISA
• Familiarity with microfluidic instruments, laboratory automation, 3D printing, advanced cell models, or conjugation reactions is a plus.

Responsibilities

• Conduct systematic experiments of in vitro transcription (IVT) reaction on benchtop bioreactors; collect and analyze the data.
• Develop and execute protocols for preparing and characterizing nucleic acid–loaded lipid nanoparticle (LNP) formulations using automated LNP synthesis platforms.
• Support LNP process development activities, including screening, scale-up, and manufacturing-relevant workflow optimization.
• Troubleshoot issues with experimental design and execution.
• Collect, analyze, and interpret experimental data; prepare technical summaries and present results in internal meetings and reviews.

Benefits

• Mentoring
• leadership programs
• internal seminar offerings
• Comprehensive onboarding, including a virtual online platform
• Mutual support, team spirit and international collaboration
• communities on numerous topics such as “Coaching”, “Agile Working” and a “Businesswomen’s Network”
• Working in smart buildings with the latest technology and equipment.

What This Job Offers

• Career Level: Intern