Laboratory Sciences Professional (Open Rank)

University of Colorado•Aurora, CO

8d•Onsite

About The Position

The University of Colorado Anschutz Medical Campus Department of Pediatrics, Section of Pediatric Critical Care, is seeking a full-time Intermediate or Senior Laboratory Sciences Professional for a research program investigating the mechanistic drivers of pulmonary vascular diseases across the lifespan and the role of redox signaling in disease. The successful candidate will contribute to laboratory investigations and serve as lab manager in a collaborative, translationally oriented research environment. The position works across in vivo mouse models, cell- and tissue-based assays, and advanced molecular techniques such as flow cytometry, spatial transcriptomics, and single-cell sequencing. The role includes conducting experiments using mouse models of pulmonary hypertension and primary cell culture, along with flow cytometry, ELISA, Western blotting, immunohistochemistry, and microscopic analysis. The employee will oversee day-to-day lab operations, ordering and financial records, inspections and equipment servicing, database accuracy, data analysis, project records, and protocol organization. Additional work includes developing laboratory protocols and potentially supervising trainees and onboarding and training new personnel. The position is based onsite in the Research Complex 2 building on the Anschutz Medical Campus in Aurora, Colorado. At the Intermediate level, the employee collaborates with investigators and stakeholders, performs and analyzes experiments, supports sample testing and documentation, manages daily lab operations, provides research animal care as needed, maintains records, assists with compliance and process improvements, develops or modifies laboratory techniques, and trains junior team members. At the Senior level, responsibilities also include developing protocol-specific systems and documentation such as process flows, training manuals, and SOPs; identifying operational-efficiency issues; and providing laboratory science expertise and leadership in study design, oversight, data management and analysis, and manuscript preparation across research activities.

Requirements

Bachelor’s degree in biology, molecular biology, chemistry, genetics, or a related field, or a combination of education and related technical/paraprofessional experience substituted on a year-for-year basis.
Intermediate level: one year of professional-level research experience.
Senior level: two years of professional-level research experience.
Intermediate level: proficient knowledge of basic laboratory techniques, including safety procedures and techniques.
Senior level: advanced knowledge of laboratory techniques, including safety procedures and techniques.
Ability to communicate effectively in writing and orally.
Ability to establish and maintain effective working relationships with employees at all levels throughout the institution.
Outstanding customer service skills.
Knowledge of basic human anatomy, physiology, and medical terminology.
Ability to interpret and master complex research protocol information.
Legally authorized to work in the United States without requiring sponsorship; sponsorship or employment authorization will not be provided now or in the future.
Willingness and ability to pass national criminal and sex offender background checks.
Successful completion of a 10-panel drug screen through Children’s Hospital Colorado when required.

Nice To Haves

Intermediate level: master’s degree in biology, molecular biology, chemistry, genetics, or a related field.
Intermediate level: two years of experience in an experimental or wet laboratory.
Senior level: master’s degree in biology, molecular biology, chemistry, genetics, or a related field.
Senior level: three years of experience in an experimental or wet laboratory.
Experience with models of lung disease.
Experience with flow cytometry and/or advanced molecular techniques.
Experience developing and troubleshooting new laboratory protocols.
Experience maintaining a database and organizing a laboratory as lab manager.
Experience training students and fellows.

Responsibilities

Collaborate with and support Principal Investigators and other stakeholders in laboratory and research functions.
Perform laboratory experiments using pulmonary hypertension mouse models, primary cell culture, and molecular and biochemical techniques, including transfections, ELISA, Western blotting, immunohistochemistry, flow cytometry, biochemical assays, and microscopic analysis.
Tabulate and analyze research data and support pre-analytical, analytical, and post-analytical testing processes, including sample preservation and preparation, result review, documentation, and communication.
Oversee daily laboratory operations, including ordering and stocking materials, maintaining equipment and inspection schedules, and ensuring laboratory safety, cleanliness, organization, and maintenance.
Provide animal care related to research studies as necessary; small-rodent work excludes genotyping and colony management.
Transport and maintain samples, documents, materials, and results as needed, and dispose of laboratory materials and samples according to established guidelines.
Review, complete, and process logs, documents, databases, and related information; maintain organized data, project records, and laboratory protocols.
Research laboratory or operational issues and assist in developing recommendations and implementing policies, practices, procedures, and quality-improvement initiatives.
Develop, troubleshoot, and implement new or modified laboratory techniques and protocols.
Assist with compliance with applicable laws, rules, and regulations, escalating issues or seeking guidance when required.
Train and assist junior team members; train or supervise junior lab members in bench work as appropriate.
Onboard and train new laboratory personnel as appropriate.
At the Senior level, develop or assist in developing protocol-specific systems and documentation, including process flows, training manuals, and standard operating procedures.
At the Senior level, provide laboratory science expertise and leadership in study design, study oversight, data management, data analysis, and manuscript preparation, and serve as a resource to investigators and stakeholders.
At the Senior level, identify operational-efficiency issues and share findings with leadership.