Laboratory Sciences Professional (Open Rank)

University of Colorado • Aurora, CO

1d • $52,030 - $75,373 • Onsite

About The Position

The University of Colorado Anschutz Medical Campus Department of Pediatrics, Section of Pediatric Critical Care, seeks a full-time Intermediate or Senior Laboratory Sciences Professional to contribute to a research program investigating the mechanistic drivers of pulmonary vascular diseases across the lifespan and the role of redox signaling in disease. The successful candidate will conduct laboratory investigations and manage the lab, working with in vivo mouse models, cell- and tissue-based assays, and advanced molecular techniques such as flow cytometry, spatial transcriptomics, and single-cell sequencing in a collaborative, translationally oriented research environment. The position is based onsite in the Research Complex 2 building on the Anschutz Medical Campus in Aurora, Colorado.

The role includes experimental work with mouse models of pulmonary hypertension and primary cell culture, as well as flow cytometry, ELISA, Western blotting, immunohistochemistry, molecular biology, biochemical assays, and microscopic analysis. Lab management duties include ordering and stocking supplies; maintaining equipment, financial records, databases, protocols, and project documentation; coordinating inspections and equipment servicing; and supporting lab safety, organization, and cleanliness. The professional also participates in data analysis, develops and troubleshoots laboratory protocols, and may train or supervise students and other lab personnel. Senior-level responsibilities additionally include leadership and expertise in study design and oversight, data management and analysis, manuscript preparation, and development of protocol-specific systems and documents.

Requirements

• Bachelor’s degree in biology, molecular biology, chemistry, genetics, or a related field; a combination of education and related technical or paraprofessional experience may substitute year for year.
• Intermediate level: at least one year of professional-level research experience.
• Senior level: at least two years of professional-level research experience.
• Applicants must be legally authorized to work in the United States without requiring current or future sponsorship.
• Must be willing and able to pass national criminal and sex offender background checks.
• Must successfully pass a 10-panel drug screen through Children’s Hospital Colorado if required for the position.
• Intermediate level: proficient knowledge of basic laboratory techniques and safety procedures.
• Senior level: advanced knowledge of laboratory techniques and safety procedures.
• Ability to communicate effectively in writing and orally and establish and maintain effective working relationships with employees at all levels.
• Outstanding customer service skills and knowledge of basic human anatomy, physiology, and medical terminology.
• Ability to interpret and master complex research protocol information.
• Experience with models of lung disease.
• Experience with flow cytometry and/or advanced molecular techniques.
• Experience developing and troubleshooting laboratory protocols.
• Experience maintaining a database and organizing a laboratory as lab manager.
• Experience training students and fellows.

Nice To Haves

• Intermediate level: master’s degree in biology, molecular biology, chemistry, genetics, or a related field.
• Intermediate level: two years of experience in an experimental or wet laboratory.
• Senior level: master’s degree in biology, molecular biology, chemistry, genetics, or a related field.
• Senior level: three years of experience in an experimental or wet laboratory.

Responsibilities

• Collaborate with and support principal investigators and other stakeholders on laboratory and research functions.
• Perform research experiments using mouse models of pulmonary hypertension, primary cell culture, and other laboratory techniques.
• Conduct molecular and biochemical research, including transfections, ELISA, Western blotting, immunohistochemistry, molecular biology, flow cytometry, biochemical assays, and microscopic analysis.
• Perform and support pre-analytical, analytical, and post-analytical testing processes, including sample preservation and preparation, and document, communicate, and evaluate results.
• Tabulate and analyze research data and help organize data and maintain accurate databases and project records.
• Manage daily laboratory operations, including ordering and stocking materials, maintaining equipment and records, and ensuring laboratory safety, cleanliness, and organization.
• Coordinate laboratory inspections and annual equipment servicing and maintain laboratory protocols.
• Provide animal care related to research studies and conduct small rodent (mouse) work, excluding genotyping and colony management.
• Transport and maintain samples, results, documents, materials, and other items as needed; dispose of laboratory materials and samples according to established guidelines.
• Review, complete, and process laboratory logs, documents, databases, and related information.
• Identify laboratory solutions, develop and troubleshoot new or modified techniques, and assist with process improvements and implementation of policies and procedures.
• Train junior team members and, as appropriate, supervise students and other junior lab members in bench work; onboard and train new personnel.
• At the senior level, develop or assist in developing protocol-specific systems and documents, including process flows, training manuals, and standard operating procedures.
• At the senior level, identify operational-efficiency issues and share findings with leadership.
• At the senior level, provide laboratory-science expertise and leadership in study design, study oversight, data management, data analysis, and manuscript preparation, and serve as a resource to investigators, researchers, clinicians, and other stakeholders.

Benefits

• Multiple medical plan options.
• Multiple dental plan options.
• Disability, life, and vision insurance.
• Employer contribution of 10% of gross pay to the 401(a) retirement plan.
• Accrued paid time off, including 22 vacation days per year, 15 sick days per year, and 15 holiday days per year.
• Tuition benefit available on all CU campuses.
• Reduced-rate ECO Pass for RTD bus and light rail service.
• Additional perks and programs through CU Advantage.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level