Open Rank Laboratory Sciences Professional

University of Colorado•Aurora, CO

1d•$52,030 - $75,373•Onsite

About The Position

The Department of Pediatrics, Section of Pediatric Critical Care is seeking a full-time Research Services Professional or Research Services Senior Professional to join a research program investigating the mechanistic drivers of pulmonary hypertension (PH) across the lifespan. The successful candidate will contribute to two related lines of investigation: (1) macrophage–extracellular matrix interactions that govern vascular remodeling in PH, and (2) maternal stress signaling pathways that predispose offspring to pulmonary vascular disease. This position offers the opportunity to work across in vivo mouse models, cell/tissue-based assays, and advanced molecular techniques (e.g., flow cytometry, spatial transcriptomics, single-cell sequencing) within a collaborative, translationally oriented lab environment. Responsibilities include performing experiments using mouse models of PH and primary cell culture, as well as flow cytometry, ELISA, Western blot, immunohistochemistry, and microscopic analysis. The role also involves maintaining an accurate database, participating in data analysis, and managing project records and protocol organization. Additional responsibilities include developing new lab protocols and, potentially, supervising trainees (students) and training new lab personnel. The ideal candidate is reliable, personable, highly motivated, and organized, with a demonstrated ability to work independently when appropriate. This is an excellent opportunity to join a fast-paced, diverse, and productive research group. The position is based in the Research Complex 2 building on the Anschutz Medical Campus.

Requirements

Bachelor’s degree in biology, molecular biology, chemistry, genetics, or related field
A combination of education and related technical/paraprofessional experience may be substituted for the bachelor’s degree on a year-for-year basis
One (1) year of professional-level research experience (Intermediate Level)
Two (2) years of professional-level research experience (Senior Level)
Proficient knowledge of basic laboratory techniques, including safety procedures and techniques (Intermediate Level)
Ability to communicate effectively, both in writing and orally
Ability to establish and maintain effective working relationships with employees at all levels throughout the institution
Outstanding customer service skills
Demonstrated commitment and leadership ability to advance diversity and inclusion
Knowledge of basic human anatomy, physiology, and medical terminology
Ability to interpret and master complex research protocol information
Experience with models of lung disease
Experience with flow cytometry and/or advanced molecular techniques
Experience developing and troubleshooting new laboratory protocols
Experience maintaining a database and organizing a lab as lab manager
Experience training students and fellows
Advanced knowledge of laboratory techniques, including safety procedures and techniques (Senior Level)
Applicants must be legally authorized to work in the United States without requiring sponsorship.
Must be willing and able to pass national criminal and sex offender background checks
Must successfully pass a 10-panel drug screen through Children’s Hospital Colorado

Nice To Haves

Master’s degree in biology, molecular biology, chemistry, genetics, or related field (Intermediate Level)
Two (2) years of experience in an experimental or wet laboratory (Intermediate Level)
Master’s degree in biology, molecular biology, chemistry, genetics, or a related field (Senior Level)
Three (3) years of experience in an experimental or wet laboratory (Senior Level)

Responsibilities

Collaborate with and support Principal Investigators (PI) and other stakeholders with laboratory and research functions
Utilize a variety of laboratory techniques required for research projects
Perform experiments and tabulate and analyze research data
Support the analytical testing process using standard lab support knowledge in the collection and review of conditions, including preserving samples, completing sample preparation, documenting and communicating results
Perform pre-analytical, analytical, and post-analytical test processes and evaluate results produced
Prepare lab for daily operations, including stocking materials, equipment, safety, cleanliness, and related areas
Provide animal care related to research studies, as necessary
Pick up, transport, and maintain results, samples, documents, materials, and other items as needed
Dispose of laboratory materials and samples using well-established guidelines and instructions
Review, complete, and process logs, documents, databases, and related materials and information
Provide support researching issues and developing recommendations to resolve process, unit and related issues
Assist in the review and implementation of lab support policies, practices, and programs to meet organizational, operations, and management needs
Assist with ensuring compliance with applicable laws, rules and regulations; receive guidance and direction or escalate when required
Independently and creatively identify laboratory solutions
Independently Review, develop, and implement new or modified laboratory techniques required for research projects
Assist Team Leads, Supervisors and/or management with creation and implementation of processes and procedures and quality improvement initiatives
Assist and train junior team members
Assist with developing or develop protocol-specific systems and documents including process flows, training manuals, and Standard Operating Procedures (SOPs). Maintains subject-level documentation and prepares documents, equipment, and/or supplies
Assist with identifying issues related to operational efficiency and share results with leadership
Provide laboratory science expertise and leadership in study design, study oversight, data management, data analysis and manuscript preparation to assist all levels of investigators, researchers and clinicians on new research activities across a wide range of disciplines
Serve as a resource to PIs and other stakeholders
Perform basic laboratory studies, including: Molecular and Biochemical research; cell culture, transfections, ELISA, Western blot, immunohistochemistry, molecular biology, flow cytometry, biochemical assays, microscopic analysis, small rodent (mouse) work excluding genotyping and colony management
Train/supervise junior lab members in bench work
Contributing to organization and overall maintenance of lab
Organization of data
Overseeing maintenance of lab equipment
Maintaining lab protocols
Training new lab personnel as appropriate