Laboratory Operations Lead

Epicrispr Biotechnologies•South San Francisco, CA
•$85,000 - $100,000

About The Position

Epicrispr Biotechnologies is seeking a highly organized and solutions-oriented Laboratory Operations Lead to support the operational infrastructure of its growing research and development organization. The role coordinates laboratory operations, procurement, vendor relationships, equipment, and environmental health and safety activities to help ensure laboratories operate safely, efficiently, and in compliance with applicable requirements. The successful candidate will work cross-functionally with R&D and other internal teams, evaluate operational needs, improve processes, and independently identify practical solutions supporting the company’s evolving research programs. This role is suited to someone who enjoys working in a dynamic biotech environment, managing multiple priorities, building efficient processes, and addressing operational challenges cost-effectively. The position is based in South San Francisco, California, and reports to the Lab Manager.

Requirements

  • Bachelor's degree in a relevant scientific, technical, laboratory operations, or related field.
  • 2–4+ years of relevant experience; biotechnology, pharmaceutical, life sciences, or related research experience is preferred.
  • Experience with laboratory operations, procurement, purchasing, vendor management, or laboratory infrastructure.
  • Experience or familiarity with laboratory biosafety, EH&S, compliance, or risk assessments.
  • Familiarity with laboratory equipment maintenance and technical service providers.
  • Experience developing or implementing laboratory processes, SOPs, or operational procedures.
  • Strong organizational, project management, and problem-solving skills.
  • Ability to manage multiple priorities in a fast-paced environment and work independently under general direction.
  • Strong communication and interpersonal skills, with the ability to work effectively with scientists, vendors, contractors, and cross-functional partners.
  • Ability to evaluate alternatives, make sound recommendations, and identify opportunities for process improvement and cost savings.
  • Strong attention to detail and commitment to safety, compliance, and operational excellence.

Nice To Haves

  • Familiarity with molecular biology, biochemistry, synthetic biology, cell culture, or another biological discipline.
  • Relevant experience in biotechnology, pharmaceutical, life sciences, or a related research environment.

Responsibilities

  • Coordinate day-to-day operations across BSL-1, BSL-2, CMC, cell biology, virus, and other research laboratories.
  • Evaluate laboratory operational needs and recommend equipment, supplies, services, and other resources.
  • Lead laboratory procurement, including sourcing and evaluating vendors, obtaining quotes, negotiating where appropriate, managing purchase orders, and reconciling orders.
  • Develop and maintain relationships with laboratory suppliers, equipment vendors, service providers, and other external partners.
  • Coordinate laboratory equipment installation, maintenance, calibration, repairs, and service activities.
  • Develop and maintain laboratory SOPs, processes, and documentation supporting safe, compliant, and efficient operations.
  • Support laboratory EH&S, biosafety, and risk-management activities, including risk assessments, SDS/MSDS documentation, waste management, and related compliance requirements.
  • Monitor laboratory practices and identify opportunities to improve safety, compliance, efficiency, and cost effectiveness.
  • Partner with R&D, Finance, Facilities, IT, Legal/Compliance, and other teams to resolve operational issues and support business needs.
  • Provide guidance and training to employees on laboratory equipment, processes, and operational procedures.
  • Research and recommend suppliers, equipment, products, and services based on scientific and operational needs.
  • Support laboratory expansion, implementation of new capabilities, and other operational projects.
  • Use discretion and independent judgment to evaluate operational alternatives, resolve issues, and make recommendations to management.
  • Perform other duties and special projects as needed.
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