Lab Manager, Platform

Aether BiomachinesMenlo Park, CA
Onsite

About The Position

We’re seeking an experienced Lab Manager to own day-to-day lab operations for our platform team. This role is responsible for ensuring our platform lab runs reliably and efficiently as experimental throughput scales. You’ll take full ownership of inventory/ordering, freezer/sample tracking, and EHS/safety, while coordinating equipment maintenance and vendor relationships. You’ll partner closely with scientists to remove operational bottlenecks in workflows involving protein expression, purification, and screening. This is primarily a no-bench role, with the option to support light lab work (e.g., preparing stock solutions, maintaining shared reagents) depending on background and interest.

Requirements

  • Bachelor’s degree in biochemistry, molecular biology, or related life sciences field.
  • 5-8+ years of experience in biology lab operations or management, ideally supporting protein/enzyme workflows.
  • Strong familiarity with protein science environments (expression, purification, assays, or screening workflows).
  • Experience implementing or managing LIMS and/or freezer/sample tracking systems.
  • Proven ownership of inventory systems, especially for temperature-sensitive and high-turnover reagents.
  • Experience managing lab equipment and coordinating service contracts.
  • Demonstrated ownership of EHS/safety programs in a lab setting.
  • Strong organizational and communication skills; able to manage complexity across multiple lab locations.

Nice To Haves

  • Experience in high-throughput or automated screening environments.
  • Hands-on familiarity with protein purification systems or assay development workflows.
  • Comfort stepping into light lab support when needed.

Responsibilities

  • Own end-to-end procurement and inventory for protein workflows: buffers, media, resins, enzymes, assay kits, consumables, and plastics.
  • Build and maintain systems for freezer and sample tracking, including lot/expiry tracking, storage mapping, and chain-of-custody.
  • Implement and manage LIMS for reagents, samples, and shared assets.
  • Establish pars, forecasting, and replenishment workflows aligned with high-throughput screening and assay needs.
  • Coordinate maintenance, calibration, and repair of biology platform instrumentation, such as liquid handlers/automation systems, plate readers, incubators and shakers, centrifuges, PCR/qPCR systems, protein purification systems, and freezers and cold storage infrastructure.
  • Ensure all equipment is well-maintained, calibrated, and audit-ready with complete documentation.
  • Track dependencies such as gases, buffers, columns, and assay materials.
  • Own and drive EHS and biosafety practices for the biology labs.
  • Maintain SOPs, SDS documentation, and chemical/biological inventories.
  • Coordinate safety training, audits, and compliance activities.
  • Oversee waste management (biological and chemical) in partnership with vendors.
  • Ensure labs meet high standards for safe, organized, and compliant operation.
  • Manage vendor relationships across reagents, equipment, service contracts, and waste disposal.
  • Negotiate and track contracts, renewals, and SLAs; maintain budget visibility.
  • Create & foster a high-functioning platform lab environment: clear labeling, organized storage, and intuitive workflows.
  • Lead onboarding for lab users (systems, inventory, safety practices, how to get things done).
  • Build lightweight SOPs, documentation, and dashboards to support self-service and reproducibility.
  • Prepare and maintain stock solutions, buffers, and shared reagents.
  • Support general lab readiness for protein and assay workflows.
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