Health Economics & Outcomes Research Associate Director

Vertex Pharmaceuticals•Boston, MA

About The Position

The Health Economics & Outcomes Research (HEOR) Associate Director participates in leading the development and execution of health economics and outcomes research studies supporting Vertex products. The role provides technical HEOR expertise, applies strategic and content knowledge to evidence-generation planning, and helps ensure research is technically and scientifically rigorous and aligned with HEOR best practices. The Associate Director gathers and synthesizes insights from payers, key opinion leaders, and HEOR experts; stays current with scientific and policy trends; and works with internal teams to generate and disseminate evidence. The role partners with Global Pricing and Market Access on global value dossiers and value narratives and collaborates with medical communications teams on publication strategy. Vertex encourages continuous learning about advances in AI, technology, automation, and industry trends, and seeks employees who thoughtfully adopt new capabilities to improve decision-making, innovation, efficiency, and outcomes for patients. The position is hybrid-eligible or on-site eligible. In the hybrid designation, employees may work remotely up to two days per week; in the on-site designation, employees work on-site five days per week with ad hoc flexibility. Flex status is subject to company policy and may change. The role has a base salary range of $204,000–$306,000 and is eligible for an annual bonus and annual equity awards. Vertex describes its benefits as including medical, dental, and vision coverage; generous paid time off, including a week-long summer and winter company shutdown; educational assistance programs, including student loan repayment; a commuting subsidy; matching charitable donations; and a 401(k).

Requirements

  • Advanced degree (PhD, MD, master's degree, MPH, or PharmD) in a relevant discipline.
  • Typically eight years of experience, with a substantial background in HEOR, or an equivalent combination of education and experience.
  • Strong track record of publication in peer-reviewed journals.
  • Technical HEOR expertise and the ability to formulate and lead creative research projects, ensuring technically and scientifically rigorous conduct that reflects best HEOR practices.
  • Strong verbal and written communication skills, including presentation skills; ability to communicate difficult concepts, persuade others, and adapt presentations to varied audiences.
  • Ability to apply knowledge of the U.S. healthcare system, global health technology appraisal requirements, and clinical development to identify evidence gaps and formulate evidence-generation strategies.
  • Understanding of the pharmaceutical industry's legal and regulatory environment, with a spotless history of compliance and ethical workplace conduct.

Responsibilities

  • Lead others in executing complex HEOR evidence-generation work, including cost-effectiveness analyses and budget impact models, prospective and retrospective observational studies, indirect treatment comparisons, meta-analyses and systematic reviews, patient-reported outcome measure development and validation, and other research supporting asset value.
  • Gather and synthesize insights from payers, key opinion leaders, and HEOR experts; monitor scientific and policy trends and best practices; and apply strategic and content expertise to strategy planning.
  • Apply best practices and provide key input to the design of Vertex observational research studies.
  • Collaborate with medical communications teams on publication strategy and ensure HEOR evidence is disseminated in a timely manner and has maximum impact.
  • Partner closely with Global Pricing and Market Access to support production of global value dossiers and value narratives.
  • Stay informed about advances in AI, technology, automation, and industry trends, and thoughtfully adopt capabilities that improve decision-making, innovation, efficiency, and patient outcomes.

Benefits

  • Medical insurance
  • Dental insurance
  • Vision insurance
  • Generous paid time off, including a week-long company shutdown in the summer and winter
  • Educational assistance programs, including student loan repayment
  • Commuting subsidy
  • Matching charitable donations
  • 401(k)
  • Annual bonus eligibility
  • Annual equity awards
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