Global Medical Lead, Neurometabolic

ITF Therapeutics•Concord, MA

1d•Remote

About The Position

The Global Medical Lead (GML), Neurometabolic is the strategic and medical/scientific owner of global medical affairs activities across the neurometabolic portfolio. The role leads end-to-end global medical strategy, evidence-generation plans, and lifecycle medical activities for programs spanning early development through commercialization. As the senior medical affairs leader for the franchise, the GML drives integrated medical strategy, cross-functional alignment, worldwide scientific engagement, and development and implementation of medical plans across geographies. The role connects global, regional, and local medical teams and is accountable for advancing scientific understanding, supporting optimal clinical use, and improving patient outcomes. The GML develops and maintains Global Medical Plans aligned with integrated evidence-generation plans, defines scientific pillars and evidence priorities, and leads clinical, real-world, health economics and outcomes, and observational evidence strategy. The role also oversees scientific dissemination, including congresses, publications, communications, medical education, and advisory boards; represents the franchise externally; and leads global KOL engagement. The GML works with cross-functional partners on launch readiness, lifecycle planning, label expansion, post-approval evidence, and development-stage asset planning. In a global matrix environment, the role guides regional and local colleagues, mentors medical colleagues, oversees governance and scientific integrity, and contributes to global medical initiative budgets. Regular international travel is required.

Requirements

Advanced scientific or medical degree required; MD, PhD, or PharmD strongly preferred.
8–15+ years of Medical Affairs, Clinical Development, or related biopharmaceutical experience.
Significant experience in rare disease required.
Demonstrated success developing and executing global medical strategies.
Proven expertise in evidence generation, scientific communications, and stakeholder engagement.
Strong experience interacting with international KOLs, investigators, and scientific experts.
Demonstrated ability to lead complex cross-functional teams and influence without direct authority.
Experience operating effectively within matrix organizations and high-growth environments.
Willingness and ability to travel internationally on a regular basis.

Nice To Haves

Neurometabolic, neurological, genetic, metabolic, pediatric, or specialty disease experience.
Experience supporting both development-stage and commercial-stage assets.
Experience preparing for or supporting global product launches.
Prior global or regional medical affairs leadership experience.

Responsibilities

Serve as the enterprise medical lead for the Neurometabolic Franchise and own global medical strategy, scientific narrative, and lifecycle medical planning.
Develop and maintain Global Medical Plans and align them with integrated evidence-generation plans.
Partner with Global Asset Leadership and the Head of Global Medical Affairs to align medical strategy with portfolio and enterprise priorities.
Define scientific pillars, messaging platforms, evidence-generation priorities, and insight-gathering strategies across development stages.
Lead medical strategy for programs from early clinical development through launch readiness and commercialization, adapting plans as assets progress.
Lead the global strategy and scientific rationale for clinical, real-world, health economics and outcomes research, and observational evidence generation.
Collaborate with Clinical Development, Biometrics, Regulatory Affairs, Value & Access, and Evidence Generation teams to address clinical, regulatory, payer, and stakeholder needs.
Identify evidence gaps and develop plans to address unmet scientific and clinical questions.
Oversee global data dissemination, including congress strategy, publications planning, scientific communications, medical education, and advisory boards.
Represent the neurometabolic franchise as a scientific and medical spokesperson at scientific meetings, advisory boards, investigator meetings, and external collaborations.
Lead global KOL engagement and scientific advisory planning, and build relationships with international thought leaders, investigators, patient advocacy groups, academic partners, and healthcare stakeholders.
Maintain expertise in neurometabolic diseases, emerging science, competitive intelligence, treatment paradigms, and patient needs.
Partner with cross-functional teams on global launch strategy and readiness, medical launch planning and execution, label expansion, lifecycle management, post-approval evidence generation, and development-stage asset planning.
Ensure medical insights inform development, access, and commercial decision-making.
Lead and influence cross-functional and cross-regional teams; guide regional and local medical colleagues and support collaboration across US, European, and international stakeholders.
Mentor and develop medical colleagues, support future medical capabilities and organizational growth, and foster scientific excellence and accountability.
Lead governance processes for franchise medical strategy, evidence review, and scientific communications.
Ensure medical activities comply with global regulatory, legal, and ethical standards and maintain scientific rigor, compliance, and transparency.
Oversee scientific interactions and partnerships with academic institutions, investigators, registries, consortia, advocacy groups, and external vendors.
Contribute to budget development and management for global medical initiatives and establish processes for efficient global execution with regional flexibility.
Travel internationally on a regular basis.