Global Medical Lead, Neurometabolic

ITF Therapeutics•Concord, MA

8h•$295,000 - $380,000•Remote

About The Position

The Global Medical Lead (GML), Neurometabolic is the strategic and medical/scientific owner of global medical affairs activities across the neurometabolic portfolio. The role leads end-to-end global medical strategy, evidence generation plans, and lifecycle medical activities for programs spanning early development through commercialization. As the senior medical affairs leader for the franchise, the GML drives integrated medical strategy, cross-functional alignment, worldwide scientific engagement, and implementation of medical plans across geographies. The GML connects global, regional, and local medical teams to support coherent execution, knowledge flow, and scientific excellence, while advancing scientific understanding, supporting optimal clinical use, and improving patient outcomes. The role requires experience across early clinical development and launch/commercialization readiness, along with the ability to build scientific strategy in complex and evolving rare disease environments. The position reports to the VP/Head of Global Medical Affairs, Rare Disease and is remote. The base compensation range is $295,000–$380,000, determined using factors including relevant skills and experience, job location, and internal equity.

Requirements

Advanced scientific or medical degree required; MD, PhD, or PharmD strongly preferred.
8–15+ years of Medical Affairs, Clinical Development, or related biopharmaceutical experience.
Significant rare disease experience required.
Demonstrated success developing and executing global medical strategies.
Expertise in evidence generation, scientific communications, and stakeholder engagement.
Strong experience interacting with international KOLs, investigators, and scientific experts.
Ability to lead complex cross-functional teams and influence without direct authority.
Ability to operate effectively within matrix organizations and high-growth environments.
Willingness and ability to travel internationally on a regular basis.

Nice To Haves

Neurometabolic, neurological, genetic, metabolic, pediatric, or specialty disease experience.
Experience supporting both development-stage and commercial-stage assets.
Experience preparing for or supporting global product launches.
Prior global or regional medical affairs leadership experience.

Responsibilities

Serve as the enterprise medical lead for the Neurometabolic Franchise, owning global medical strategy, scientific narrative, and lifecycle medical planning.
Develop and maintain Global Medical Plans and align them with integrated evidence generation plans.
Partner with Global Asset Leadership and the Head of Global Medical Affairs to align medical strategy with portfolio priorities and enterprise objectives.
Define scientific pillars, messaging platforms, evidence-generation priorities, and insight-gathering strategies across development stages.
Lead medical strategy for programs from early clinical development through launch readiness and commercialization, evolving plans as assets progress.
Lead global strategies and scientific rationales for clinical, real-world evidence, HEOR, and observational evidence-generation activities.
Collaborate with Clinical Development, Biometrics, Regulatory Affairs, Value & Access, and Evidence Generation teams to address clinical, regulatory, payer, and stakeholder needs.
Identify evidence gaps and develop plans to address unmet scientific and clinical questions.
Oversee global data dissemination, including congress strategy, publication planning, scientific communications, medical education, and advisory boards.
Serve as a primary scientific and medical spokesperson for the neurometabolic franchise and represent the organization at scientific meetings, advisory boards, investigator meetings, and external collaborations.
Lead global KOL engagement and scientific advisory planning to inform medical strategy, evidence priorities, and lifecycle decisions.
Build and maintain relationships with international thought leaders, investigators, patient advocacy groups, academic partners, and healthcare stakeholders.
Maintain expertise in neurometabolic diseases, emerging science, competitive intelligence, treatment paradigms, and evolving patient needs.
Develop scientific platforms and communication strategies that support long-term franchise objectives.
Partner with Regulatory Affairs, Clinical Development, Market Access, HEOR, Safety, non-promotional Commercial, and Portfolio Strategy teams on integrated lifecycle planning.
Lead medical contributions to global launch strategy and readiness, medical launch planning and execution, label expansion, lifecycle management, post-approval evidence generation, and development-stage asset planning.
Ensure medical insights inform development, access, and commercial decision-making.
Lead and influence cross-functional and cross-regional teams in a global matrix environment, providing strategic guidance to regional and local medical colleagues.
Drive collaboration among US, European, and international stakeholders and build partnerships across medical, commercial, clinical, and development organizations.
Support development of future medical capabilities and organizational growth; mentor medical colleagues and foster scientific excellence and accountability.
Lead governance processes for franchise medical strategy, evidence review, and scientific communications.
Ensure medical activities comply with global regulatory, legal, and ethical standards and maintain rigor, compliance, and transparency in evidence generation and medical affairs.
Oversee scientific interactions and partnerships with academic institutions, investigators, registries, consortia, advocacy groups, and external vendors.
Contribute to budget development and management for global medical initiatives and establish efficient global execution processes that allow regional adaptation.