Sr. Director, Medical Affairs, Neurometabolic Team

ITF Therapeutics•Concord, MA

13h

About The Position

The Senior Director, Medical Affairs, Neurometabolic Team leads U.S. Medical Affairs strategy for ITF Therapeutics’ rare neurometabolic disease portfolio. Reporting to the Vice President of U.S. Medical Affairs & Patient Advocacy, this role is the senior U.S. medical leader for the portfolio and translates global medical strategy into effective U.S. plans and launch execution. As a member of the U.S. Medical Affairs leadership team, the Senior Director provides strategic and scientific leadership across product development and commercialization, including U.S. medical strategy, launch readiness, scientific engagement, field medical effectiveness, medical communications, education, payer engagement, and cross-functional execution. Working closely with the Global Medical Director, the Senior Director represents the U.S. medical perspective for the neurometabolic portfolio and ensures global evidence generation, scientific communications, and medical activities address the needs of U.S. patients, healthcare professionals, payers, and other stakeholders. The role calls for rare disease expertise, strong scientific and strategic leadership, and the ability to influence within a matrixed global organization. The leader will foster scientific excellence, collaboration, patient centricity, and innovation, while helping establish ITF Therapeutics as a trusted partner in the neurometabolic community.

Requirements

MD, PharmD, or PhD in a relevant scientific, medical, or healthcare discipline.
12+ years of progressive pharmaceutical or biotechnology experience within Medical Affairs, Clinical Development, or related functions.
Demonstrated success leading U.S. Medical Affairs organizations and launch readiness activities for rare disease and/or specialty products.
Experience partnering effectively with Global Medical Affairs teams in a matrixed multinational organization.
Proven ability to influence global strategy through U.S. market insights, external stakeholder engagement, and evidence generation planning.
Strong understanding of evidence generation, publication planning, scientific communications, medical governance, and healthcare decision-making processes.
Significant experience engaging KOLs, researchers, advocacy organizations, payers, and healthcare systems.
Demonstrated ability to operate strategically while driving flawless execution.

Nice To Haves

Experience in neurometabolic disease or lysosomal storage diseases.
Experience supporting product launches and pre-launch Medical Affairs activities.
Expertise in neurometabolic disorders, rare diseases, neuroscience, genetics, or related therapeutic areas.
Experience with insight generation, customer engagement platforms, and CRM systems.
Demonstrated success managing departmental budgets and resource planning.
Experience working in a global or matrixed organizational environment.

Responsibilities

Lead development and execution of integrated U.S. Medical Affairs strategies and tactical plans across pre-launch, launch, and lifecycle stages for the neurometabolic portfolio.
Serve as the senior U.S. medical leader for target neurometabolic diseases, supporting patient identification, disease and product knowledge, and improved patient outcomes.
Lead U.S. medical launch planning and execution, including readiness plans for field medical, scientific communications, medical education, insight generation, congresses, advisory boards, and stakeholder engagement.
Partner with Commercial, Market Access, Regulatory, Patient Advocacy, Global Medical Affairs, and Clinical Development to coordinate launch execution; identify and mitigate launch risks and address opportunities and competitive dynamics.
Lead U.S. scientific communication and medical education strategies, including congress activities, scientific exchange, educational programs, and content development.
Align U.S. communication plans with global publication and evidence dissemination strategies; review and approve U.S. medical materials to address stakeholder educational needs.
Drive insight generation and translate stakeholder insights into recommendations for development, launch, and lifecycle strategies.
Provide U.S. strategic input into evidence generation priorities, study concepts, real-world evidence initiatives, publication planning, and data dissemination.
Monitor scientific, clinical, regulatory, policy, and competitive developments to inform decisions.
Build and maintain relationships with KOLs, investigators, healthcare professionals, patient advocacy organizations, professional societies, payers, and other stakeholders.
Lead advisory boards and expert consultations to inform medical strategy and evidence priorities; represent ITF Therapeutics at scientific, advocacy, and industry forums.
Partner with Market Access and HEOR on evidence demonstrating clinical, economic, and patient-centered value; support payer-facing medical engagements and patient access objectives.
Serve as a strategic partner to Commercial, Clinical Development, Regulatory Affairs, Market Access, Safety, Patient Advocacy, and Global Medical Affairs, providing scientific leadership across business decisions and strategic initiatives.
Act as the primary U.S. partner to the Global Neurometabolic Medical Director, contributing U.S. market insights to disease and product strategy, lifecycle planning, evidence generation, publication priorities, and scientific platform development.
Align U.S. and global stakeholders, incorporating U.S. insights into global plans while maintaining scientific integrity and patient focus.
Build, lead, and develop a high-performing U.S. Medical Affairs neurometabolic team; coach and mentor team members and foster accountability, collaboration, innovation, and scientific excellence.
Establish team priorities, performance expectations, and development plans to support organizational growth and succession planning, and promote a patient-centered culture.