Global Clinical Trial Leader

Roche • South San Francisco, CA

7d • $125,100 - $232,300 • Hybrid

About The Position

As a Global Clinical Trial Leader (CTL) within Genentech Research and Early Development (gRED), you will be accountable for the operational execution and global delivery of pioneering early development clinical trials (Phases I and II) under the leadership of the Senior CTL. You will contribute directly to the cross-functional Protocol Execution Team (PET), translating scientific discoveries into operational plans for molecular entities with limited or no prior clinical data. You will provide clinical operational expertise throughout study start-up, conduct, and close-out for one or more global cross-functional PETs. The role is based in South San Francisco and follows a hybrid schedule with three days per week on campus. Relocation benefits are not available. The expected salary range for the primary location in California is $125,100.00–$232,300.00 USD. Actual pay depends on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. The position also qualifies for the benefits detailed through the provided benefits link.

Requirements

• Bachelor’s degree or equivalent; a scientific or healthcare discipline is preferred.
• At least 4 years of clinical study management experience in a biopharma or CRO environment.
• Working knowledge of ICH/GCP guidelines, international regulatory frameworks, and early clinical drug development processes.
• Hands-on experience managing operational aspects of complex global Phase I or Phase II clinical studies.
• Proven expertise in clinical trial execution, cross-functional team collaboration, and study vendor oversight.

Nice To Haves

• Direct experience in early-phase clinical development in oncology, immunology, infectious disease, or neuroscience.
• Demonstrated experience managing specialized vendors, such as central labs, specialty bioanalytical labs, imaging, and interactive response technology (IRT), as well as decentralized or digital trial technologies.
• A track record of thriving in ambiguous, fast-paced environments that require adaptive study designs and rapid protocol amendments.

Responsibilities

• Provide clinical operational expertise across study start-up, conduct, and close-out for one or more global cross-functional Protocol Execution Teams.
• Drive and finalize critical trial deliverables, including vendor specifications, investigational product drug supply forecasting, monitoring plans, Trial Master File quality, and Clinical Trial Management System data integrity.
• Collaborate with and influence multidisciplinary study teams to gather strategic input on study plans, country and site feasibility assessments, and investigator meeting execution.
• Participate in vendor identification and selection with the PET Leader, and manage delegated outsourced CRO activities to ensure delivery aligns with contracted scope, timelines, and budgets.
• Contribute operational feasibility insight to clinical protocol and informed consent document design, anticipating challenges unique to early-stage human trials.
• Monitor critical-path study milestones, identify risks proactively, implement mitigation plans, and propose solutions to complex trial bottlenecks.
• Foster an inclusive, high-trust, and accountable project environment across local and global cross-functional partners to support reliable, high-quality trial delivery.

Benefits

• A discretionary annual bonus may be available based on individual and Company performance.
• The position qualifies for the benefits detailed at the provided benefits link.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level