Global Clinical Trial Leader

Genentech • Daly City, CA

7d • $125,100 - $232,300 • Hybrid

About The Position

As a Global Clinical Trial Leader (CTL) within Genentech Research and Early Development (gRED), you will be accountable for the operational execution and global delivery of early development Phase I and II clinical trials under the leadership of the Senior CTL. You will contribute to the cross-functional Protocol Execution Team (PET), translating scientific discoveries into operational plans for molecular entities with limited or no prior clinical data.

The role provides clinical operational expertise across study start-up, conduct, and close-out. It drives critical trial deliverables, supports cross-functional study planning and feasibility, and oversees delegated outsourced CRO activities to ensure delivery within contracted scope, timelines, and budgets. The CTL also contributes operational insight to protocol and informed consent design, monitors study milestones and risks, and fosters an inclusive, accountable environment to support reliable, high-quality trial delivery.

The position is based in South San Francisco with a hybrid schedule of three days per week on campus. Relocation benefits are not available. The expected salary range for the primary California location is $125,100 to $232,300 USD. Actual pay depends on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and company performance. The position qualifies for company benefits detailed at the provided link.

Requirements

• Bachelor’s degree or equivalent; a scientific or healthcare discipline is preferred.
• At least 4 years of clinical study management experience in biopharma or CRO environments.
• Working knowledge of ICH/GCP guidelines, international regulatory frameworks, and early clinical drug development processes.
• Hands-on experience managing operational aspects of complex global Phase I or Phase II clinical studies.
• Proven expertise in clinical trial execution, cross-functional team collaboration, and study vendor oversight.

Nice To Haves

• Direct experience in oncology, immunology, infectious disease, or neuroscience early-phase clinical development.
• Experience managing specialized vendors, including central labs, specialty bioanalytical labs, imaging, and interactive response technology (IRT), as well as decentralized or digital trial technologies.
• A track record of thriving in ambiguous, fast-paced environments requiring adaptive study designs and rapid protocol amendments.

Responsibilities

• Provide clinical operational expertise across study start-up, conduct, and close-out to one or more global cross-functional Protocol Execution Teams.
• Drive and finalize trial deliverables, including vendor specifications, investigational product drug-supply forecasts, monitoring plans, Trial Master File quality, and Clinical Trial Management System data integrity.
• Collaborate with and influence multidisciplinary study teams on study plans, country and site feasibility assessments, and investigator meeting execution.
• Participate in vendor identification and selection with the PET Leader, and manage delegated outsourced CRO activities to ensure alignment with contracted scope, timelines, and budgets.
• Contribute operational feasibility insight to clinical protocol and informed consent document design, anticipating challenges specific to early-stage human trials.
• Monitor critical-path study milestones, identify risks, implement mitigation plans, and propose solutions to trial bottlenecks.
• Foster an inclusive, high-trust, accountable environment across local and global cross-functional partners.

Benefits

• Company benefits are referenced via a link in the posting, but specific benefits are not listed.
• A discretionary annual bonus may be available based on individual and company performance.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level