Executive Director, Commercial Analytics — Global Forecasting

Vertex Inc. • Boston, MA

1d

About The Position

The Executive Director, Commercial Analytics — Global Forecasting leads Vertex’s integrated global forecasting capability within Global Commercial Strategy, with accountability for forecast quality, consistency, and strategic use across the portfolio. The scope covers early pipeline, pre-launch, launch, lifecycle, and in-line products. This senior enterprise leadership role establishes forecasting standards, governance, methodologies, and organizational talent.

The role owns the annual Long-Range Planning (LRP) revenue forecasting process in partnership with Global Commercial Strategy leadership, Corporate Finance, disease leaders, regions, and Manufacturing and Supply Chain. It integrates disease-area forecasts into a global revenue outlook and translates that outlook into portfolio, investment, demand, capacity, and supply-planning implications. The Executive Director also develops the forecasting organization, tools, processes, and governance, and communicates clear recommendations and uncertainties to senior leaders.

Requirements

• Minimum bachelor’s degree in business, economics, finance, statistics, mathematics, operations research, life sciences, engineering, or a related discipline.
• Extensive leadership experience in biopharmaceutical forecasting, commercial analytics, strategic planning, or a closely related discipline.
• Demonstrated success leading forecasting across a broad portfolio that includes in-line products and pipeline assets at multiple development stages.
• Deep expertise in global revenue forecasting, patient-based and market-based models, scenario planning, uncertainty assessment, analog selection, assumption development, and model governance.
• Significant experience leading long-range planning and partnering with senior Commercial and Corporate Finance leaders on portfolio, investment, and enterprise planning decisions.
• Experience integrating global, regional, and local forecasting processes and reconciling near-term operational forecasts with long-range strategic forecasts.
• Experience partnering with Manufacturing and Supply Chain and translating commercial forecasts into demand, capacity, and supply-planning implications.
• Experience supporting commercialization decisions across early pipeline, pre-launch, launch, lifecycle management, and established in-line businesses.
• Demonstrated ability to establish forecasting standards, common methodologies, governance, tools, and quality controls across a complex global organization.
• Proven success building and leading high-performing forecasting teams through senior leaders and influencing effectively in a highly matrixed environment.
• Exceptional strategic judgment, analytical rigor, financial and commercial acumen, executive communication, and ability to constructively challenge assumptions while building alignment.

Nice To Haves

• An advanced degree such as an MBA, M.S., Ph.D., or other relevant qualification.

Responsibilities

• Lead the Global Forecasting organization and capability agenda across pipeline, pre-launch, launch, lifecycle, and in-line disease areas.
• Own the integrated global revenue outlook for the Vertex portfolio and its underlying market, patient, access, competitive, clinical, regulatory, pricing, and commercial assumptions.
• Co-lead the annual LRP revenue forecasting process with Global Commercial Strategy leadership and Corporate Finance, establishing its process, calendar, deliverables, governance, and executive decision points.
• Integrate disease-area forecasts into a coherent portfolio view and communicate value drivers, sensitivities, risks, opportunities, uncertainties, and investment implications.
• Establish enterprise forecasting standards for model architecture, assumptions, scenarios, documentation, quality control, version management, reviews, and approvals.
• Connect global and regional forecasting processes, aligning assumptions and clarifying transitions and accountabilities between near-term in-line and longer-range global forecasts.
• Partner with Manufacturing and Supply Chain to translate commercial forecasts into demand and capacity-planning inputs, including scenarios, ranges, timing, and updates at material inflection points.
• Refresh forecasts when material clinical, regulatory, competitive, access, market, or supply information changes the outlook or the decisions it supports.
• Develop base, upside, downside, and alternative scenarios to quantify uncertainty and inform strategic, portfolio, launch, capital-allocation, and supply decisions.
• Integrate evidence from Market Research, Decision Science, Competitive Intelligence, epidemiology, HEOR, Value & Access, Medical, Development, and external data sources.
• Provide objective forecasting leadership to disease teams and senior governance forums, pressure-test assumptions, and translate complex outputs into clear recommendations.
• Establish forecasting approaches suited to different lifecycle stages, from early opportunity assessment and commercial due diligence through launch and mature in-line products.
• Build scalable forecasting tools, templates, data structures, and reporting mechanisms that improve transparency, comparability, agility, and reuse.
• Select and manage external forecasting partners when specialized capacity is needed while maintaining internal ownership of methods, assumptions, interpretation, and quality.
• Build, develop, and retain a high-performing global forecasting team.
• Measure forecast performance, process effectiveness, stakeholder confidence, and decision impact, and use lessons learned to improve models, standards, and ways of working.

Benefits

• Annual bonus eligibility
• Annual equity awards
• Medical, dental, and vision benefits
• Generous paid time off, including a week-long company shutdown in the summer and winter
• Educational assistance programs, including student loan repayment
• Commuting subsidy
• Matching charitable donations
• 401(k)

What This Job Offers

• Job Type: Full-time
• Career Level: Executive