Executive Director, Clinical Program Lead

Insmed Incorporated•NJ Corporate Headquarters, NJ

9d•$306,000 - $417,000•Hybrid

About The Position

At Insmed, every moment and every patient counts — and so does every person who joins in. As a global biopharmaceutical company dedicated to transforming the lives of patients with serious and rare diseases, you’ll be part of a community that prioritizes the human experience, celebrates curiosity, and values every person’s contributions to meaningful progress. That commitment has earned us recognition as Science magazine’s No. 1 Top Employer for five consecutive years, certification as a Great Place to Work® in the U.S., and a place on The Sunday Times Best Places to Work list in the UK. For patients, for each other, and for the future of science, we’re in. Are you? About the Role: We’re looking for an Executive Director, Clinical Program Lead (CPL) to help us expand what’s possible for patients with serious diseases. Reporting to the Clinical Therapeutic Area Head, Respiratory, the Executive Director, CPL will provide clinical leadership for a respiratory asset across late Phase 2 and Phase 3b development. This role is a core member of the Global Project Team (GPT) and leads the Global Clinical Team, overseeing physicians and clinical scientists responsible for study design, execution, safety oversight, and supporting regulatory engagements.

Requirements

MD or MD/PhD
10+ years of clinical development experience in biotech or pharma
Late-stage program leadership across small molecules and biologics
Demonstrated leadership of global Phase 2–3b programs, including clinical strategy, execution, and data interpretation.
Strong knowledge of global regulatory pathways and interactions (FDA, EMA, PMDA).
Proven ability to lead and influence in complex, matrixed, cross-functional organizations.
Exceptional written and verbal communication skills with scientific, regulatory, and executive stakeholders.
Strategic clinical judgment and scientific rigor.
Ability to influence and act decisively within matrixed environments.
Executive-level communication and external presence.
Ability to navigate ambiguity and drive timely, high-quality decisions.
Commitment to patient safety, data integrity, and ethical standards.

Nice To Haves

Board certification in Pulmonary or Allergy strongly preferred.
Combination drug–device experience focusing on respiratory diseases strongly preferred.

Responsibilities

Own and maintain the global Clinical Development Plan (CDP) aligned to the Target Product Profile (TPP) and portfolio strategy.
Serve as clinical lead on the cross-functional GPT, accountable for all clinical strategy and deliverables.
Provide senior medical oversight of global studies, including benefit–risk assessment, safety signal management, and clinical input to regulatory interactions (FDA, EMA, PMDA).
Lead the design of mid-to-late-stage clinical trials ensuring compliance with ICH-GCP, ethical standards, and global regulatory requirements.
Build, lead, and develop a high-performing global clinical team of physicians and scientists to support current and future programs.
Establish and maintain strategic relationships with key external experts, investigators, and advisors supporting the development program.

Benefits

Comprehensive medical, dental, and vision coverage
Mental health support
Annual wellbeing reimbursement
Access to our Employee Assistance Program (EAP)
Generous paid time off policies
Fertility and family-forming benefits
Caregiver support
Flexible work schedules with purposeful in-person collaboration
401(k) plan with a competitive company match
Annual equity awards
Participation in our Employee Stock Purchase Plan (ESPP)
Company-paid life and disability insurance
Company Learning Institute providing access to LinkedIn Learning, skill building workshops, leadership programs, mentorship connections, and networking opportunities
Employee resource groups
Service and recognition programs
Meaningful opportunities to connect, volunteer, and give back