Entrepreneur-in-Residence (EIR), AlphaLab

Innovation Works, Inc.•Pittsburgh, PA

34d•Hybrid

About The Position

The Entrepreneur-in-Residence (EIR) will work directly with AlphaLab founders and our accelerator team during the core program cycle. This is a hands-on strategic role where the EIR will engage deeply with company teams, help founders identify and work through their most important business challenges, and bring experienced operating judgment to decisions around commercialization, customers, partnerships, capital, and company strategy. The expectation is not simply to offer advice, but to quickly understand a company, identify what matters most, challenge assumptions, help founders prioritize, and work alongside teams to move critical initiatives forward. The role has a particular depth supporting healthcare-focused companies.

Requirements

Significant entrepreneurial or early-stage operating experience in healthcare, life sciences, physical products, robotics, software, or a related field.
Firsthand experience building, leading, or holding a senior operating role in an early-stage company.
Strong judgment around company strategy, commercialization, customer development, fundraising, partnerships, and go-to-market.
Familiarity with industry-specific issues such as regulatory pathways, clinical validation, reimbursement, or healthcare stakeholder dynamics.
Demonstrated ability to quickly understand complex businesses and help founders identify the decisions and actions that matter most.
Comfortable challenging assumptions and providing direct, thoughtful feedback.
Able to move fluidly between strategic thinking and hands-on execution.
Strong communicator who can build credibility and trust with founders.
Organized, collaborative, reliable, and able to operate effectively in a fast-moving accelerator environment.

Responsibilities

Build strong working relationships with cohort companies and become a trusted strategic resource to founders.
Participate in regular 1:1 company meetings and help teams identify their most important near-term priorities, risks, and milestones.
Work directly with founders on customer discovery, commercialization strategy, go-to-market planning, partnerships, fundraising, and company positioning.
Help teams translate broad strategic goals into clear priorities, decisions, experiments, and next steps.
Pressure-test business models, market assumptions, customer hypotheses, pricing, channel strategies, and growth plans.
Provide candid, practical feedback on difficult company-building decisions and help founders evaluate tradeoffs.
Identify gaps in strategy or execution and work with founders and Program Managers to determine where deeper support is needed.
Support companies preparing for major milestones such as customer pilots, strategic partnerships, fundraising, regulatory progress, or market entry.
Bring healthcare and life sciences perspective to company strategy where relevant, including commercialization pathways, clinical validation, reimbursement, regulatory considerations, and stakeholder dynamics.
Connect founders with relevant customers, experts, investors, operators, and industry partners when those relationships can materially advance the company.
Learn and apply AlphaLab’s Defined Accelerator Playbook while contributing experienced operator perspective to the program.
Work closely with Program Managers to assess company progress and determine where targeted intervention can have the greatest impact.
Support and help lead founder-facing programming, including strategy sessions, pitch practice, investor preparation, storytelling, data room development, and deck reviews.
Translate recurring company challenges into useful discussions, workshops, or resources for the broader cohort.
Participate in internal team discussions about company progress, founder needs, and program priorities.
Help ensure founders receive practical, coordinated, and high-quality support throughout the accelerator.