Discovery Scientist I

Cleveland Clinic

3d•Onsite

About The Position

The Discovery Scientist I works within Cleveland Clinic’s Center for Experimental Therapeutics, a cross-functional research team that uses small molecules, biologics, automated systems, and advanced technologies to move early drug discovery projects toward clinical development. This is a non-patient-facing role involving the design and execution of experiments, development of modern drug discovery expertise, data analysis, and contributions to scientific presentations. The scientist collaborates with experienced mentors and multidisciplinary colleagues in a setting that values diverse perspectives in team decision-making. The role includes routine tissue culture, automated cell-based assays, chemical biology assays for target engagement, and compound management for high-throughput screening. The scientist also maintains laboratory equipment, records and reports experimental data, manages laboratory inventories and supplies, contributes to publications and patent applications, and may assist in training technicians, trainees, and students. The position is based at Cleveland Clinic Main Campus in Cleveland and works days, 8:00 a.m. to 5:00 p.m.

Requirements

Bachelor's degree in a relevant scientific field.
Entry-level, with 0–2 years of relevant experience.
Excellent verbal and technical communication skills.
Strong interpersonal skills.

Nice To Haves

Undergraduate thesis or research experience in an organic chemistry laboratory, with exposure to synthetic methodology or synthesis.
Research experience in a biology or biochemistry laboratory, or other related experience with demonstrated leadership.
Prior hands-on laboratory experience in cell biology or molecular biology.

Responsibilities

Perform required Center standard operating procedures with minimal supervision.
Demonstrate consistent quality and accuracy in daily work.
Follow laboratory safety and compliance policies and procedures.
Collaborate with an experienced scientific mentor to design and execute experiments.
Assist with troubleshooting and identifying potential solutions to laboratory challenges.
Calculate, record, compile, and report experimental data.
Maintain electronic laboratory notebooks with minimal supervision.
Address problems related to daily laboratory activities.
Maintain laboratory inventories and order materials as needed.
Demonstrate proficiency in using laboratory instruments and equipment.
Maintain instrumentation and equipment for daily use in accordance with training and established procedures.
Contribute to publications, manuscripts, and patent applications.
Assist in training technicians, trainees, and students as needed.
Participate in team meetings and collaborate in a multidisciplinary environment, including with Cleveland Clinic collaborators, to discuss research and contribute ideas.
Perform routine tissue culture.
Help establish and routinely perform automated cell-based assays in accordance with standard operating procedures.
Help establish chemical biology assays for target engagement studies.
Assist with compound management for high-throughput screening using automated liquid handlers, automated compound storage systems, and integrated informatics systems to track compounds.
Manage laboratory reagents and supplies and maintain a clean, safe, and organized working environment.
Perform other duties as assigned.