Director, Transformation Enterprise Program Office

Worldwide Clinical TrialsResearch Triangle Park, NC
$145,500 - $288,500

About The Position

This is an opportunity to help a world-class specialty Contract Research Organization (CRO) bring its deep scientific expertise to new customers and new markets. The Director, Transformation Enterprise Program Office is a pivotal role within the Enterprise Program Management Office (EPMO). This position acts as the strategic partner and driving force for a dedicated portfolio of EPMO projects. Each lead has a distinct area of deep expertise: Change Management: Focused on organizational readiness, stakeholder engagement, and adoption of new processes and tools. Contract Research Organization (CRO) Operations: Focused on enabling underlying process and technology improvements in a CRO context. Technology Delivery: Focused on guiding project teams to implement new technology across the enterprise. Each Portfolio Lead will own and manage a portfolio of high-impact initiatives within their area of expertise, serving as the single point of contact for project teams. They will drive proactive planning, problem-solving, capability building, and progress tracking to ensure the successful execution and value realization of the portfolio. While each role has a dedicated focus area, the Portfolio Leads will operate as a cohesive team, collaborating to align their portfolios, share insights, resolve cross-cutting issues, and contribute to the overall success of the EPMO. A Portfolio Lead may have direct reports. This team-based approach ensures that projects benefit from multidisciplinary expertise and a unified approach to execution. The ideal candidate is a master facilitator, strategist, and coach with deep expertise in their domain (Change Management, CRO Operations, or Technology Implementation), a strong track record of navigating complexity, and the ability to support and enable project leaders to succeed.

Requirements

  • Exceptional leadership and facilitation skills, with the ability to influence, motivate, and align cross-functional teams toward a common vision
  • Advanced strategic thinking, capable of synthesizing complex information and developing actionable plans that drive enterprise value
  • Outstanding communication abilities, both written and verbal, with a proven aptitude for preparing executive-level documentation and delivering high-impact presentations
  • Superior problem-solving and critical thinking skills, able to anticipate risks, analyze challenges from multiple perspectives, and implement effective solutions quickly
  • Strong organizational acumen, including the ability to manage multiple projects simultaneously and prioritize competing demands in a dynamic environment
  • Deep proficiency in project and portfolio management methodologies, Transformation Office techniques, tools, and best practices
  • High emotional intelligence and the ability to foster a culture of trust, engagement, and continuous improvement
  • Change management expertise, with a knack for guiding organizations through ambiguity and transformation
  • Flexible and adaptable, thriving in fast-paced, evolving environments, and embracing opportunities to innovate and learn
  • Technological curiosity and literacy, especially as it relates to emerging trends in Artificial Intelligence (AI) and digital transformation
  • Bachelor’s degree in Finance, Economics, Accounting, Business Administration, Engineering, or a related field
  • Minimum of 5 years of Contract Research Organization (CRO) and Life Sciences experience
  • Minimum of 12 years of experience in strategy execution, business transformation, digital program management, portfolio management, software technology implementation, change management, or a similar role within a large-scale EPMO or Transformation Office
  • Proven track record of managing a portfolio of complex projects and achieving strategic objectives
  • Demonstrated ability to identify and resolve complex organizational and project-related challenges
  • Strong executive presence with experience presenting to and communicating with senior leadership
  • Expertise in change management principles and their practical application in a corporate environment
  • Exceptional coaching, mentoring, and influencing skills
  • Adept at navigating complex global organizations
  • Familiarity with AI concepts and their application in business is highly desirable
  • Excellent written and verbal communication skills; able to influence and align stakeholders from frontline teams to executive leadership

Nice To Haves

  • Master’s degree or certifications in Agile, Change Management, or Lean Six Sigma are a plus

Responsibilities

  • Serve as the single point of contact for all projects within the assigned EPMO portfolio
  • Proactively engage with and support project teams to monitor progress and ensure the successful delivery of intended value and outcomes
  • Collaborate with Project Leaders to refine overall project plans, including the establishment of critical milestones and success metrics
  • Identify, analyze, and help resolve significant blockers to project success, such as lack of stakeholder alignment, fear of change, organizational capability gaps, etc.
  • Prepare and develop clear, concise documentation for executive- and board-level governance meetings
  • Lead comprehensive post-mortems to capture lessons learned and foster a culture of continuous improvement
  • Integrate the assigned portfolio of projects into the overall EPMO, ensuring alignment with broader enterprise objectives
  • Coach and mentor Project Leaders on best practices for executing successful, high-impact projects
  • Champion and guide the integration of Artificial Intelligence (AI) into project methodologies and solutions
  • Act as a key enabler of critical resources and support to Project Leaders, including access to expert interviews, targeted research, and analytical support
  • May supervise direct reports, supporting their performance and development
  • Perform other duties as assigned. The duties and responsibilities listed above are representative of the nature and level of work assigned and are not necessarily all-inclusive.

Benefits

  • Competitive benefits package
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