Director, Human Resources Business Partner

Vertex Inc.•Boston, MA

1d•Hybrid

About The Position

We are seeking a strategic, influential, and agile HR Business Partner Director to lead talent strategies for key G&A functions at Vertex. This Director will play a critical role in achieving the vision of enhancing leadership, driving innovation, enabling top-tier execution, and integrating technology to achieve superior performance across a diverse development pipeline. This role will serve as a trusted advisor to G&A leaders and their teams, shaping organizational design, culture, and workforce strategies that enable innovation, execution and long-term success. This role shapes and executes talent strategies that strengthen leadership, enable excellence, and supports Vertex’s mission to bring transformative therapies to patients.

Requirements

Proven ability to design and activate enterprise‑level HR and talent strategies that drive measurable business impact
Expert capability in strategic workforce planning, from insight generation and scenario modeling through execution
Deep expertise in talent management, succession planning, leadership development, and career architecture
Demonstrated leadership in large‑scale organizational change, culture evolution, and enterprise transformation initiatives
Advanced understanding of leadership effectiveness, employee relations, inclusive talent practices, and the application of workforce analytics to business decisions
Bachelor's degree in human resources or related, relevant discipline
10 years of progressive HR experience or the equivalent combination of education and experience

Responsibilities

Acts as a strategic advisor and coach to senior leaders, influencing business and talent decisions through deep understanding of the operating environment, enterprise priorities, and external trends
Uses advanced data, analytics, and external insight to identify emerging workforce and capability trends; translates complexity into clear, compelling narratives that inform decision‑making, challenge assumptions, and drive action
Architects and leads integrated talent and organizational strategies that proactively address future capability needs, leadership gaps, and operating model evolution
Advises leaders on complex organization design, workforce transformation, and change leadership initiatives to enable agility, scale, and sustained performance
Shapes and executes enterprise‑aligned talent strategies to attract, develop, and retain critical skills and diverse leadership pipelines at all levels
Leads strategic workforce planning to align near‑ and long‑term talent supply with business strategy, including capability forecasting, succession planning, and scenario planning
Partners with HR Centers of Excellence (Total Rewards, Talent Acquisition, Talent Management, Strategic People Analytics, Employee Services & Global Operations) to deliver cohesive, high‑impact solutions and elevate the overall employee experience
Oversees and evolves core people processes (e.g., performance, talent reviews, compensation planning) to ensure they drive accountability, growth, and business outcomes—not just compliance
Partners with Talent Acquisition to shape forward‑looking hiring strategies aligned to critical capability builds, with a strong focus on diverse talent, pivotal roles, and board‑approved hires