Director, HTA, Value & Evidence (HV&E) - Rare Disease

Pfizer • New York City, NY

3d • Hybrid

About The Position

Pfizer’s Health Technology Assessment, Value & Evidence (HV&E) team works to support affordable, timely patient access to medicines and vaccines by advancing value and evidence solutions for healthcare decision-making. The Director, HTA, Value & Evidence (HV&E) – Rare Disease supports the Rare Disease Division’s strategic goals by driving optimal patient access for Hympavzi (marstacimab) and guiding global evidence development. The role oversees evidence-generation activities and technical deliverables, including health economics and outcomes research (HEOR), in partnership with global, regional, country, and cross-functional teams.

The Director leads the global evidence-generation strategy and HEOR studies from concept through publication; coordinates local and regional evidence needs; and develops launch and lifecycle materials to support reimbursement and access. The role also contributes to patient-reported outcomes and clinical-trial evidence strategy, advises on trial designs and analyses, supports compliant dissemination of HEOR materials, and develops external research partnerships. The position is hybrid, requiring work on site 2 to 3 days per week, and may involve domestic and international travel based on business needs. Relocation assistance may be available based on business needs and/or eligibility.

Requirements

• Graduate degree, such as MSc, MPH, PhD, or DrPH.
• At least 7 years of experience with an MSc/MPH/MBA, or at least 5 years with a PharmD/PhD/DrPH, in HEOR or a related field such as health economics, epidemiology, health services research, or another research-focused public health field.
• Expertise in HEOR strategy and evidence development, health services research methods and tools, health economic modeling, patient-reported outcomes, statistics, and real-world evidence studies.
• Technical and methodological knowledge of registries and observational study design, implementation, analysis, and interpretation.
• Ability to independently manage complex non-interventional study projects.
• Knowledge and understanding of the drug-development process.
• Excellent interpersonal skills and ability to understand and respond to multiple internal and external customers.
• Excellent oral and written English communication skills.
• Ability to assess anticipated project or program value, align work with business priorities, and prioritize accordingly.
• Execution mindset focused on getting work done quickly and simply.
• Strong project-management skills, including contracting, budgeting, and vendor management.
• Ability to manage multiple complex projects involving significant budgets, competing deadlines, shifting priorities, and stakeholder engagement.
• Experience leading cross-functional teams, influencing medical, clinical, and commercial teams constructively, thinking strategically, and guiding junior team members.
• Ability to function effectively in a matrix organization.
• Organization, attention to detail, proactive prioritization, and ability to anticipate and resolve needs.
• Comfort responding to change and unexpected demands under tight timelines.
• Authorization to be employed in the United States by any employer; U.S. work visa sponsorship is not available.
• Permanent work authorization in the United States.

Nice To Haves

• Knowledge of and experience in the rare disease therapeutic area.
• Experience with HTA organizations such as NICE, CADTH, PBAC, and ICER.
• Knowledge of industry trends, such as IPAY and the EU HTA Regulation.
• Publication history in peer-reviewed journals.
• Experience in the biotechnology or pharmaceutical industry.
• Experience supporting a global launch.

Responsibilities

• Lead development of the evidence-generation strategy for Hympavzi (marstacimab) with cross-functional partners.
• Coordinate input from local country and regional teams on evidence needs and incorporate it into the global evidence strategy for launch and product lifecycle market access.
• Lead the design and execution of global HEOR studies, such as network meta-analyses, non-interventional studies, and economic models, from concept through publication.
• Lead timely development of launch deliverables, including value and evidence strategies, global value dossiers, AMCP/JCA dossiers, systematic literature reviews, economic models, and tools supporting reimbursement and access.
• Develop a patient-reported outcomes strategy and incorporate humanistic and economic endpoints into clinical trials across product-development phases.
• Provide strategic input on clinical-trial designs and analyses, including patient populations, comparators, and endpoints, to support payer and regulatory discussions, reimbursement, and patient access.
• Partner with internal stakeholders to ensure customer-facing dissemination of HEOR materials follows regulatory guidance and internal SOPs.
• Develop strategic partnerships and research collaborations with external experts, healthcare policy makers, payers, and academic and community oncology settings.
• Manage HEOR projects, including contracting, budgeting, vendor management, and coordination across multiple projects and stakeholders.
• Guide junior team members and influence cross-functional teams in a matrix organization.

Benefits

• 401(k) plan with Pfizer matching contributions and an additional Pfizer Retirement Savings Contribution.
• Paid vacation, holidays, and personal days.
• Paid caregiver/parental and medical leave.
• Medical, prescription drug, dental, and vision coverage.
• Eligible to participate in Pfizer’s Global Performance Plan, with a bonus target of 20% of base salary.
• Eligible to participate in a share-based long-term incentive program.
• Relocation assistance may be available based on business needs and/or eligibility.

What This Job Offers

• Job Type: Full-time
• Career Level: Director