Director, Head of Product Management – AI-Enabled Precision Medicine (Therapeutics & Innovations)

Natera

1d•$184,600 - $230,700•Remote

About The Position

We are redefining the future of precision medicine by integrating AI with healthcare to create next-generation, precision treatment modalities. Our multidisciplinary team is building products at the intersection of clinical data, multi-omics, and machine learning—unlocking entirely new approaches to drug development and patient care. Within the Therapeutics & Innovations Business Unit, we are developing a new category that bridges diagnostics and therapeutics. Our platform combines deep scientific expertise with proprietary datasets to power AI-enabled solutions that can transform how therapies are discovered, developed, and deployed. We are looking for a product leader who can translate this potential into real, scalable products—owning the strategy, roadmap, and execution to bring these innovations to market.

Requirements

Advanced degree (PhD, MD, MS, or equivalent) in life sciences, bioengineering, computational biology, or related field preferred.
8–12+ years of experience in product management, product strategy, or related roles in biotech, life sciences, or healthcare technology.
Proven track record of building and launching complex, data-driven products.
Strong understanding of drug development workflows and/or clinical diagnostics.
Experience working with AI/ML-driven products or data platforms is highly preferred.
Exceptional ability to translate complex science into clear product decisions and strategies.
Demonstrated success leading cross-functional teams in ambiguous environments.
Strong commercial acumen, including product-market fit, pricing, and partnership models.

Nice To Haves

Experience with biomarker development, oncology, or precision medicine.
Background in diagnostics + therapeutics integration.
Experience in early-stage or high-growth environments.

Responsibilities

Define and own the product vision and roadmap for AI-enabled tools for precision medicine offerings (e.g., biomarkers, trial enablement tools, co-development platforms) via genomic language models, biomedical AI agents, AI-driven analysis platforms, forecasting algorithms.
Identify high-value use cases across drug development (e.g., trial design, patient selection, translational insights, companion diagnostics).
Translate platform capabilities into clear product strategies aligned with business goals.
Lead the end-to-end product lifecycle: concept → validation → build → launch → iteration.
Partner with R&D, data science, and engineering to define product requirements and ensure high-quality execution.
Drive prioritization decisions across competing opportunities based on impact, feasibility, and strategic alignment.
Engage with biopharma partners, clinicians, and internal stakeholders to deeply understand needs and workflows.
Synthesize customer insights into product requirements and roadmap decisions.
Continuously assess market trends, competitive landscape, and emerging technologies.
Serve as the central hub across Product, R&D, Clinical, BD, and Marketing.
Align stakeholders around a unified product strategy and execution plan.
Drive decision-making in a matrixed, fast-moving environment.
Partner with commercial and BD teams to define product positioning, packaging, and pricing.
Support go-to-market strategy, including pilot programs, partnerships, and scaled deployments.
Ensure successful product launches with clear value propositions and supporting evidence.
Define requirements for product validation, including analytical, clinical, and real-world evidence.
Ensure products meet scientific, regulatory, and commercial expectations.
Partner with clinical and regulatory teams to align product strategy with approval pathways where applicable.
Build and mentor a high-performing product management function.
Establish product processes, operating cadence, and best practices.
Foster a culture of ownership, speed, and scientific rigor.