Director, GTO Digital Transformation

AstraZeneca • Gaithersburg, MD

6d • $172,466 - $258,700 • Hybrid

About The Position

The Director, GTO Digital Initiatives leads the day-to-day delivery of priority digital transformation initiatives within the GTO digital portfolio. This role converts portfolio priorities into executable delivery plans, coordinates matrixed contributors, strengthens governance and delivery field, and provides portfolio management support to the Senior Director, GTO Digital Transformation. The initial anchor program for this role is the Biologics workstream within the OPS2030 Digital Tech Transfer initiative, including associated pilots and scale-readiness activities. Over time, the role may also support other GTO digital initiatives requiring senior delivery leadership, transformation field, and cross-functional coordination.

Requirements

• Bachelor’s degree in Engineering, Life Sciences, Pharmaceutical Sciences, Biotechnology, Information Systems, Data Science, Business, or a related field.
• Minimum 10+ years of experience
• Demonstrated experience in pharmaceutical, biotechnology, manufacturing, technical operations, digital transformation, program delivery, or related areas.
• Demonstrated experience leading complex, matrixed digital transformation programs in manufacturing, technical operations, tech transfer, process development, MS&T, quality, data, or other regulated environments.
• Strong program and project management capabilities with the ability to lead teams and workstreams without direct line authority.
• Strong financial management skills, including experience with forecasts, actual spend, accruals, vendor status, purchase orders, cross-charges, and delivery tracking.
• Understanding of technical operations and digital transformation in regulated environments.
• Strong customer management, facilitation, executive communication, risk management, and escalation skills.
• Collaborative, low-ego operating style with the ability to work effectively within a defined role scope while providing senior delivery leadership.

Nice To Haves

• Advanced degree such as MBA, MS, PhD, PharmD, or equivalent experience.
• Experience in Biologics tech transfer lifecycle, including drug substance, drug product, analytical, manufacturing readiness, and quality/regulatory considerations.
• Experience with enterprise data strategy, domain modeling, semantic technologies, ontologies, data governance, knowledge management, or digital manufacturing platforms.
• Experience with AI, GenAI, analytics, automation, digital manufacturing, or Industry 4.0 initiatives in regulated environments.
• Experience partnering with PMO, Enterprise Data, Architecture, IT, consulting partners, and cross-functional business teams.

Responsibilities

• Lead delivery execution: Lead day-to-day delivery of assigned GTO digital initiatives, beginning with the Biologics Digital Tech Transfer workstream and growing to other priority initiatives as portfolio needs evolve.
• Manage pilots and workstreams: Own planning, execution, achievement tracking, risk management, dependency management, and readiness for scale for assigned pilots and workstreams.
• Translate strategy into execution: Convert priorities established by the Senior Director and governance teams into executable delivery plans, achievements, decision points, and blocking issue pathways.
• Represent Biologics requirements: Ensure Biologics requirements are represented across Development, Commercial, Alexion, and site perspectives for the initial DTT anchor program.
• Coordinate enabling partners: Partner with Data, Architecture, IT, PMO, Enterprise Data Office, and other capability teams to support foundations, domain models, semantic layers, integrations, and governance needs.
• Maintain portfolio tracking: Manage portfolio tracking, delivery cadence, status reporting, dependency views, and governance materials on behalf of the Senior Director.
• Prepare governance updates: Develop clear program and governance updates that proactively surface risks, blockers, decision needs, and resource gaps.
• Support intake and roadmap hygiene: Maintain intake subject area and roadmap updates while recognizing that prioritization, scope approval, and trade-off decisions remain with the Senior Director.
• Track initiative financials: Own forecast versus actual spend, accruals, cross-charges, vendor and purchase order status, and budget risks for assigned initiatives and workstreams.
• Track delivery performance: Maintain project and task tracking for breakthroughs, risks, actions, dependencies, resource demand, and delivery readiness.
• Provide regular reporting: Report financial and delivery status on a defined cadence without requiring repeated follow-up.
• Drive process re imagination: Advance simplification, automation, AI-enabled workflows, knowledge retention, and scalable future-state ways of working.
• Translate concepts into delivery: Convert transformation opportunities into pilots, use cases, business capabilities, delivery plans, and measurable outcomes.
• Challenge status quo: Help move programs beyond simple digitization toward redesigned, data-enabled, and AI-ready tech transfer processes.

Benefits

• short-term incentive bonus opportunity
• equity-based long-term incentive program
• retirement contribution
• commission payment eligibility
• qualified retirement program [401(k) plan]
• paid vacation and holidays
• paid leaves
• health benefits including medical, prescription drug, dental, and vision coverage

What This Job Offers

• Job Type: Full-time
• Career Level: Director