Core Technician – (Night Shift)

Lonza•Houston, TX

1d•Onsite

About The Position

The Core Technician supports GMP production of viral therapeutics through aseptic processing, including cell culture, purification, formulation, and fill/finish activities. The role also maintains cleanroom environments, prepares buffers and components, and follows cGMP standards and documentation practices. This is an on-site position in Houston, Texas, on a rotating 12-hour schedule from 7:00 PM to 7:30 AM, including weekends, to support continuous manufacturing operations. The position involves performing production tasks using manual, semi-automated, and automated equipment, supporting clinical manufacturing, and assisting with validation, troubleshooting, and changeovers. The technician works under close supervision and must maintain accurate documentation and compliance with procedures.

Requirements

Demonstrated knowledge of aseptic techniques and cGMP manufacturing environments.
Ability to follow detailed SOPs and perform tasks under close supervision while maintaining accuracy and compliance.
Familiarity with cleanroom operations, including gowning qualifications and behavior standards.
Ability to operate and support troubleshooting of manufacturing equipment.
Strong documentation skills and working knowledge of Microsoft Office applications.
Effective communication skills and ability to work both independently and in a team-based environment.
Ability to stand for extended periods and perform physically demanding gowning and cleanroom tasks.
An Associate’s degree or relevant experience is acceptable; a Bachelor’s degree in Life Sciences is preferred.

Nice To Haves

Experience with cell culture, viral production, or related bioprocessing techniques.
Bachelor’s degree in Life Sciences.

Responsibilities

Perform GMP-compliant production of viral therapeutic products, including large-scale mammalian cell culture.
Execute aseptic processing techniques across production activities such as purification, formulation, and fill/finish.
Prepare buffers and components and operate autoclaves and other process systems.
Operate manual, semi-automated, and automated production equipment to support clinical manufacturing.
Maintain cleanroom operations, including stocking, setup, and adherence to gowning procedures.
Assist in validation activities, equipment troubleshooting, changeovers, and data collection.
Support cell banking activities.
Ensure accurate documentation of all performed tasks.