Computational Chemist

Schrödinger•Cambridge, NY

About The Position

Schrödinger is seeking a Computational Chemist to join its Therapeutics Group (STG) and contribute to the discovery of therapeutics. The role is part of an interdisciplinary team of more than 60 scientists—including designers, modelers, computational and medicinal chemists, crystallographers, biochemists, and biologists—supported by more than 100 software developers and engineers and large-scale computing infrastructure. The Computational Chemist will provide modeling support to active drug discovery projects, help develop appropriate modeling approaches and methods, troubleshoot computational problems, share knowledge across STG, and collaborate with internal software development teams to improve Schrödinger’s drug discovery technologies.

Requirements

  • Ph.D. in computational chemistry or a related field.
  • Robust scientific training in molecular modeling, statistical mechanics, and/or quantum mechanics.
  • Training or experience in one or more of the following: computationally driven lead optimization, molecular dynamics, free-energy methods, machine learning, virtual ligand screening, cheminformatics, or ADMET modeling.

Nice To Haves

  • Postdoctoral or pharmaceutical/biotechnology experience in structure-based drug design.
  • Excellent communication skills and exposure to another discipline relevant to drug discovery, such as synthetic organic chemistry, pharmacology, toxicology, formulation, biochemistry, physical chemistry, or analytical chemistry.
  • Familiarity with coding or scripting languages and/or chemically aware databases.
  • Enjoys working as a team player in interdisciplinary environments.

Responsibilities

  • Provide computational chemistry and modeling support to active drug discovery projects.
  • Assist with and develop appropriate modeling approaches to help drive drug discovery projects and methods development.
  • Troubleshoot computational problems.
  • Share knowledge with the broader Schrödinger Therapeutics Group.
  • Work closely with internal software development teams to improve Schrödinger’s drug discovery technologies.

Benefits

  • Competitive salary
  • Equity-based compensation
  • Healthcare, including dental and vision
  • 401(k)
  • Pre-tax commuter benefits
  • Flexible work schedule
  • Parental leave program
  • Over a month of paid vacation time
  • Company-wide events

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What This Job Offers

Job Type

Full-time

Career Level

Senior

Education Level

Ph.D. or professional degree

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