Computational Chemist

Schrödinger•San Diego, CA

20h•$100,000 - $180,000

About The Position

Schrödinger is seeking a Computational Chemist to join the Schrödinger Therapeutics Group (STG), a team of more than 60 scientists working across drug discovery disciplines and therapeutic areas. The group is supported by more than 100 software developers and engineers and large-scale computing infrastructure. The role provides computational chemistry and modeling support to active drug discovery projects, helps develop appropriate modeling approaches and methods, troubleshoots computational problems, shares knowledge within STG, and collaborates with internal software development teams to improve Schrödinger’s drug discovery technologies. The position suits a structure-based drug designer with strong scientific training and the ability to work and communicate across disciplines. Schrödinger offers competitive salary, equity-based compensation, healthcare benefits, a 401(k), commuter benefits, flexible scheduling, parental leave, and more than a month of paid vacation. The estimated base salary range is $100,000–$180,000; actual compensation depends on factors including experience, education, market data, and business needs.

Requirements

Ph.D. in computational chemistry or a related field.
Robust scientific training in molecular modeling, statistical mechanics, and/or quantum mechanics.
Expertise in one or more of the following areas: computationally driven lead optimization, molecular dynamics, free-energy methods, machine learning, virtual ligand screening, cheminformatics, or ADMET modeling.
Strong communication and teamwork skills for working in interdisciplinary environments.

Nice To Haves

Postdoctoral or pharmaceutical/biotechnology experience.
Exposure to another drug-discovery discipline, such as synthetic organic chemistry, pharmacology, toxicology, formulation, biochemistry, physical chemistry, or analytical chemistry.
Familiarity with coding or scripting languages and/or chemically aware databases.

Responsibilities

Provide computational chemistry and modeling support to active drug discovery projects.
Assist in developing appropriate modeling approaches to help drive drug discovery projects and methods development.
Troubleshoot computational problems.
Share knowledge with the greater Schrödinger Therapeutics Group (STG).
Work closely with internal software development teams to improve Schrödinger’s drug discovery technologies.