Co-Op, Translational Immunology (6 months)

Century TherapeuticsWatertown, MA
$23 - $25Onsite

About The Position

Century Therapeutics (NASDAQ: IPSC) is a biotechnology company advancing a pipeline of induced pluripotent stem cell (iPSC)-derived cell therapies with the potential to meaningfully address autoimmune diseases, including type 1 diabetes, and cancer. The company’s therapies are derived from its iPSC cell foundry and leverage its novel immune evasion engineering technology, Allo-Evasion™. Century believes its approach to developing off-the-shelf cell therapies will expand patient access and provide advantages over existing cell therapies which will ultimately advance the course of care. Position Summary We are seeking a highly motivated and innovative co-op to support development, optimization, and fit-for-purpose qualification of flow cytometry based and molecular ddPCR assays for Phase 1 clinical studies in cell therapy, following FDA guidance for early-phase bioanalytical method development. In this role, the co-op will work closely with a small team of scientists to develop robust assays to assess clinical assets’ therapeutic performance. The student will gain hands-on experience with immune cell culture, flow cytometry, and a range of in vitro functional assays used to assess cell therapy products. These biomarker approaches will be examined through the lens of bioanalytical method industry standards. The co-op will also contribute to data analysis, interpretation, and presentation of findings to internal teams. This opportunity is ideal for a candidate who is enthusiastic about immunology, cell therapy, and translational research, and who is eager to build technical and analytical skills in a biotech environment focused on advancing innovative therapies toward the clinic.

Requirements

  • Currently enrolled in either an undergraduate or graduate level program in the biological sciences.
  • Experience with mammalian cell culture and aseptic technique
  • Familiarity with scientific software such as FlowJo, GraphPad Prism, and Microsoft Office
  • Strong organizational skills and attention to detail
  • Ability to work independently and think critically about experimental design and data
  • Motivated, curious, and passionate about immunology and translational science
  • Eagerness to contribute to research with meaningful clinical impact

Nice To Haves

  • Flow cytometry experience preferred

Responsibilities

  • Support development, optimization, and fit-for-purpose qualification of both flow cytometry–based and molecular ddPCR assays for Phase 1 clinical studies, following FDA guidance for early-phase bioanalytical method development.
  • Gain exposure to regulatory decision-making in early clinical development by contributing assay data and qualification data packages.
  • Culture and maintain tumor cells along with processing of PBMCs for assay controls.
  • Analyze, interpret, and present experimental data to internal teams.
  • Collaborate cross-functionally with scientists across all levels to advance internal research programs.
  • Maintain accurate experimental records in an electronic lab notebook and contribute to supporting documentation.
  • Participate in shared lab responsibilities to help maintain a productive research environment.
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