CMC Program Manager

Immatics • Houston, TX

1d

About The Position

Immatics is seeking a Program Manager, CMC to lead and coordinate cross-functional Chemistry, Manufacturing, and Controls activities in a cell therapy development and manufacturing environment. The role drives planning, execution, and integration across manufacturing, analytical, quality, regulatory, and supply chain functions to support clinical development and commercialization goals. It serves as a strategic partner to technical and operational teams, supporting alignment, proactive risk management, and readiness for key milestones, including regulatory submissions and commercial manufacturing. The position reports to the Director, Program Management and is located at 13203 Murphy Road, Suite 100, Stafford, TX 77477.

Requirements

• Bachelor's degree in life sciences, medicine, immunology, oncology, pharmacy, health sciences, or a related field.
• At least 5 years of experience in biotechnology, pharmaceutical, or oncology-focused clinical development environments.
• Demonstrated experience in CMC programs and projects, working cross-functionally across CMC activities including manufacturing, quality, analytical, and regulatory operations.
• Academic or industry experience in cell and gene therapy, immunology/oncology, or bioprocessing/manufacturing sciences.

Nice To Haves

• Advanced degree such as a Master's or PhD in life sciences, medicine, immunology, oncology, pharmacy, health sciences, or a related field.
• Experience supporting late-stage CMC programs in immunology, oncology, or cell and gene therapy.
• Proven experience managing programs and critical paths across multiple technical and operational functions.
• Proficiency with project management tools, dashboards, and reporting systems in regulated environments.
• Proven leadership, stakeholder management, and organizational skills, with the ability to manage competing priorities in fast-paced environments.
• Ability to identify risks, drive decision-making, and implement process improvements across cross-functional teams.
• Experience coordinating external vendors, CMOs, CDMOs, or consulting partners.
• Strong communication and presentation skills, including experience supporting senior leadership discussions and strategic planning.

Responsibilities

• Develop and maintain CMC program plans, timelines, risk registers, trackers, and reporting tools to support integrated program execution.
• Manage CMC deliverables, milestones, and critical paths while ensuring alignment with overarching development program timelines.
• Lead and facilitate cross-functional CMC meetings, including agenda development, documentation, action tracking, and follow-up activities.
• Drive collaboration across Manufacturing, Process Development, Analytical Development, Quality, Regulatory, Supply Chain, and Patient Operations teams.
• Coordinate and oversee activities with external vendors, contractors, CMOs, and CDMOs.
• Support strategic planning, governance, and decision-making activities with department leaders and senior management.
• Contribute to continuous improvement of CMC program management tools, processes, onboarding, and operational best practices.

Benefits

• Competitive rates for health, dental, and vision insurance.
• Four weeks of vacation granted up front each year, prorated for the first and last year of employment.
• 12 company-paid holidays.
• 7 days of sick time.
• 100% employer-paid life insurance up to 1x annual salary, capped at $100,000.
• 100% employer-paid short- and long-term disability coverage.
• 401(k) with immediate eligibility and company matching contributions.
• Partially paid parental leave for eligible employees.
• Voluntary employee-paid benefits and services, including accident, hospital indemnity, and critical illness insurance, identity theft protection, and pet insurance.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level