Clinical Systems Manager, Clinical Data Management

Rapport Therapeutics•Boston, MA

2d•$120,000 - $145,000•Hybrid

About The Position

The Clinical Systems Manager oversees the implementation, maintenance, optimization, and security of clinical information systems—including EDC, data warehousing and reporting tools, IRT, and eCOA—to support safe, efficient, and compliant clinical research. The role manages clinical platforms' deployment, daily operations, upgrades, and configuration, and serves as a primary liaison between clinical users and IT or software vendors. The position oversees data integrations and interfaces, maintains compliance with applicable regulatory and privacy standards, coordinates system testing and user training, develops SOPs, and manages vendors, project milestones, and system changes. The manager also serves as a business partner to Data Management, Biostatistics, Programming, Clinical Operations, Finance, and Clinical Development, promoting cross-functional collaboration and continuous improvement. The role is based in a hybrid work environment, with the team onsite at the Boston office Monday through Wednesday. Rapport also describes a lab-based full-time setting in San Diego. The company offers competitive benefits, including unlimited PTO, a lifestyle spending account, and commuting reimbursement.

Requirements

Bachelor's degree in Computer Science, Information Systems, Nursing, Life Sciences, or a related field.
4 to 7 years of combined experience in healthcare, clinical development, or IT data management, including 2+ years in a leadership or system ownership role.
Proficiency with Electronic Health Record (EHR) systems, database structures (SQL), SAS, cloud environments (AWS/GCP), and data integration standards.
Knowledge of CDASH, SDTM, data quality standards, and submission requirements.
Strong analytical, organizational, and problem-solving skills, with attention to detail.
Excellent communication and leadership skills, with the ability to influence across functions and levels.

Responsibilities

Manage deployment, daily operations, upgrades, and configuration of clinical platforms.
Serve as the primary bridge between clinical end-users and IT or software development vendors.
Oversee system interfaces, including HL7/FHIR and lab or radiology connections, to ensure accurate data flow between platforms.
Maintain adherence to HIPAA, GCP, 21 CFR Part 11, and data privacy requirements.
Coordinate testing, write Standard Operating Procedures (SOPs), and guide staff on proper system usage.
Oversee third-party software providers, track project milestones, and manage system changes.
Partner across Data Management, Biostatistics, Programming, Clinical Operations, Finance, and Clinical Development to foster collaboration and continuous improvement.