Clinical Research Assistant II Neuroscience Clinical Trials

Mass General Brigham•Boston, MA

4d•$24 - $39•Onsite

About The Position

The Idiopathic Intracranial Hypertension Treatment and Research Initiative (IIH-TRI) seeks a motivated Clinical Research Assistant II to support its translational research and clinical trial program. Projects include investigating hormonal, metabolic, and genetic factors in idiopathic intracranial hypertension (IIH) through the Harvard Biomarkers Study 2.0; analyzing MRI glymphatic transit to better understand IIH and improve diagnostic accuracy; and supporting an investigator-initiated clinical trial. The role works under the supervision of the Administrative Director of the CNCT and Principal Investigators. The position supports clinical research activities such as participant screening and recruitment, study visit scheduling, data collection and management, clinical testing, protocol development, and IRB submissions. It may involve making independent judgments about participant eligibility, recommending protocol changes, and training or overseeing less experienced staff. The role also includes maintaining detailed logs, coordinating with regulatory staff, and interacting with physicians, scientists, and allied health professionals. Most of the work is dedicated to clinical research, with exposure to clinical evaluation and basic science related to IIH. Wet-lab activities may include processing patient samples for biobanking and analyzing previously banked samples. There may be opportunities to contribute to scientific presentations and publications, take patient histories, prepare reports for attending review, and shadow clinicians.

Requirements

Bachelor's degree in science required; relevant experience may be accepted in lieu of a degree.
One to two years of relevant research and data management experience required.
Ability to work independently.
Excellent interpersonal skills for working with study participants and patients.
Good oral and written communication skills.
Analytical skills and ability to resolve technical or research problems and interpret the acceptability of data results.
High degree of computer literacy and ability or willingness to learn basic website management skills.
Excellent organizational skills and ability to prioritize a variety of tasks.
Careful attention to detail.
Ability to demonstrate professionalism and respect for subjects’ rights and individual needs.
Knowledge of data management programs.
Knowledge of clinical research protocols, including IRB regulatory documentation.

Nice To Haves

Coding skills are highly desirable.
Interest in a long-term biomedical career in medicine or clinical research.

Responsibilities

Assist research colleagues with the internal and external implementation of sponsored clinical research studies.
Initiate and maintain contact with study participants; screen applicants, assess eligibility, and make independent judgments about suitability for participation.
Develop and implement patient recruitment strategies in collaboration with the Principal Investigator and/or Research Manager.
Schedule study visits and collect, organize, maintain, and update patient and study data.
Develop, organize, and maintain study databases, including an IIH-TRI patient registry; perform data validation and quality control.
Perform clinical tests such as phlebotomy, EKGs, visual acuity testing, or clinical activity scoring, as applicable.
Support the development and implementation of research protocols, including study design, data collection systems, and institutional review board approval.
Recommend changes to research protocols.
Prepare IRB submissions, including applications, amendments, annual reviews, and adverse event reports.
Keep detailed logs of patient research visits and research activities and liaise with regulatory staff for small-scale clinical trials.
Perform literature searches as appropriate.
Assist the Principal Investigator or Research Manager with presentations and written publications.
Train and orient new staff.
Process patient samples for biobanking or conduct analyses on previously banked samples, as needed.
Perform other duties as assigned.