Clinical Research Assistant II Neuroscience Clinical Trials

Mass General Brigham • Boston, MA

3d • Onsite

About The Position

The Idiopathic Intracranial Hypertension Treatment and Research Initiative (IIH-TRI) seeks a Clinical Research Assistant II to support translational research and clinical trials. Projects include studying hormonal, metabolic, and genetic factors in idiopathic intracranial hypertension (IIH) through the Harvard Biomarkers Study 2.0; analyzing MRI glymphatic transit to investigate IIH pathophysiology and improve diagnostic accuracy; and supporting an investigator-initiated clinical trial.

The role works under the supervision of the Administrative Director of the CNCT and Principal Investigators. The assistant supports study implementation and participant recruitment, evaluates potential participants, collects and manages patient and study data, schedules visits, performs clinical tests, and assists with protocols and IRB submissions. Other work may include processing patient samples for biobanking, analyzing previously banked samples, maintaining detailed visit and activity logs, and liaising with regulatory staff. The position involves collaboration with physicians, scientists, and allied health professionals, with opportunities to contribute to scientific publications and gain exposure to clinical evaluation and basic science related to IIH.

Applicants must submit a cover letter; a biosketch, resume, or CV with GPA scores or equivalent; one recommendation letter from a professional supervisor; and contact information for three supervisors willing to provide references.

Requirements

• Bachelor's degree in science; relevant experience may be accepted in lieu of a degree.
• One to two years of relevant research and data management experience.
• Ability to work independently.
• Excellent interpersonal skills for working with study participants and patients.
• Good oral and written communication skills.
• Analytical skills and the ability to resolve technical or research problems and interpret the acceptability of data results.
• High degree of computer literacy and willingness or ability to learn basic website management skills.
• Excellent organizational skills and ability to prioritize a variety of tasks.
• Careful attention to detail.
• Ability to demonstrate professionalism and respect for subjects' rights and individual needs.
• Knowledge of data management programs.
• Knowledge of clinical research protocols, including IRB regulatory documentation.

Nice To Haves

• Coding skills.
• Interest in a long-term biomedical career in medicine or clinical research.

Responsibilities

• Assist research colleagues with implementing sponsored clinical research studies internally and externally.
• Initiate and maintain contact with study participants; screen applicants, confirm eligibility, and independently assess suitability for participation.
• Develop and implement patient recruitment strategies with the Principal Investigator and/or Research Manager.
• Schedule study visits and collect, organize, maintain, and update patient and study data.
• Perform clinical tests such as phlebotomy, EKGs, visual acuity testing, or clinical activity scoring, as applicable.
• Develop, organize, and maintain study databases, including the IIH-TRI patient registry, and conduct data validation and quality control.
• Help develop and implement research protocols, data collection systems, and IRB submissions; recommend protocol changes.
• Prepare IRB applications, amendments, annual reviews, and adverse-event submissions.
• Perform literature searches as appropriate.
• Assist the Principal Investigator or Research Manager with presentations and published articles.
• Train and orient new staff and oversee the work of more entry-level staff as applicable.
• Maintain detailed logs of research visits and activities and liaise with regulatory staff for small-scale clinical trials.
• Process patient samples for biobanking or perform analyses on previously biobanked samples, as applicable.
• Perform other duties as assigned.

Benefits

• Comprehensive benefits.
• Career advancement opportunities.
• Differentials, premiums, and bonuses as applicable.
• Recognition programs designed to celebrate contributions and support professional growth.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level