Clinical Pharmacology Consultant

Entrada Therapeutics • Boston, MA

3d • Remote

About The Position

Entrada Therapeutics is seeking a Clinical Pharmacology Consultant to provide clinical pharmacology expertise for its clinical-stage programs. The consultant will report directly to the Head of Clinical Pharmacology and work closely with functions across the organization. The role is a U.S.-based remote contract position requiring 30–40 hours of support per week.

Entrada is a clinical-stage biopharmaceutical company developing medicines intended to engage intracellular targets. Its development portfolio includes genetic medicines for neuromuscular and inherited retinal diseases, including programs for Duchenne muscular dystrophy and a partnered program for myotonic dystrophy type 1. The company describes itself as a close-knit team focused on developing therapies for patients.

Requirements

• Master’s degree with 8 or more years of experience, Ph.D. with 3 or more years of experience, or Pharm.D. or M.D. with relevant experience, in pharmaceutical sciences, pharmacology, pharmacometrics, pharmacokinetics, or a related discipline.
• Strong mathematical model development and analytical skills.
• Experience using Phoenix WinNonlin, R, NONMEM, MATLAB, or other pharmacokinetic and modeling software.

Nice To Haves

• Publication record demonstrating technical exposure to early exploratory trials through Phase 2/3 programs.
• Compartmental PK/PD modeling experience.

Responsibilities

• Provide clinical pharmacology input to regulatory documents.
• Participate in clinical study design and documentation, including lab manuals, protocols, and statistical analysis plans (SAPs).
• Independently lead and oversee the analysis, interpretation, integration, and reporting of clinical pharmacokinetic and pharmacodynamic data for assigned projects.
• Collaborate with Clinical Development, Biostatistics, Non-Clinical Product Development, Clinical Operations, and Regulatory to support project-team and corporate objectives.
• Monitor work performed by CROs and other external vendors to ensure compliance with agreed protocols, quality standards, and timelines.

What This Job Offers

• Career Level: Mid Level