Clinical Development Leader, Movement Disorders

Praxis Precision Medicines, Inc.

1d•$280,000 - $350,000•Remote

About The Position

Praxis Precision Medicines is seeking a Clinical Development Leader for their Movement Disorders portfolio. This role involves shaping development strategy, leading clinical trials from design through execution, interpreting data, driving cross-functional teams, and managing regulatory interactions. The ideal candidate will have deep expertise in movement disorders and a hands-on approach to leading clinical development efforts. This is an opportunity to take increasing ownership as the portfolio evolves within a dynamic, small, and flexible organization.

Requirements

An advanced scientific degree (MD, PharmD, PhD, or equivalent) is required.
A track record of clinical trials, programs, submissions, or major development decisions that you personally led.
Regulatory submissions ownership having carried the clinical content of IND, CTA, NDA, or MAA filings, briefing books, and health authority interactions.
Strong judgment and the ability to make thoughtful, timely calls on emerging data with incomplete information and the knowledge of what to escalate and when.
Comfort operating in a dynamic environment within a small, flexible organization where scope shifts and the role is defined by what needs doing rather than by a job description.
Take ownership, challenge assumptions with scientific rigor, move with urgency without sacrificing quality, and stay focused on outcomes that matter for patients.

Responsibilities

Movement disorders development: Apply deep understanding of the disease area, endpoints, rating instruments, and patient experience to development strategy and decision-making.
Clinical strategy and trials: Translate science, emerging data, patient need, and regulatory requirements into development strategies and personally lead studies from design through execution.
Data-driven decisions: Interpret emerging clinical and scientific data, identify what matters, and make timely calls when information is incomplete.
Regulatory strategy: Own substantive clinical content for regulatory filings, briefing materials, and health authority interactions.
Cross-functional leadership: Drive teams across clinical operations, biostatistics, regulatory, safety, and other disciplines to resolve issues and move programs forward.
External leadership: Represent Praxis credibly with investigators, KOLs, health authorities, and partners.