Chief Medical Officer

XRHealth•Needham, MA

33d•Onsite

About The Position

The Chief Medical Officer is XRHealth’s senior clinical leader and is accountable for all medical and clinical-related activities across the company. Reporting to the CEO and serving on the executive leadership team, the CMO sets clinical strategy, owns quality and patient safety, governs the clinical use of AI, builds the evidence base behind the company’s products, and serves as the external clinical voice with payers, health systems, partners, regulators, and investors. This is a hands-on, build-and-scale role for a physician with a technology mindset. The ideal candidate has built or scaled the clinical function of a digital health company, can translate clinical insight into product decisions, and understands how evidence and outcomes drive enterprise and payer adoption. The role is based in, or requires willingness to relocate to, the Boston area, with regular office work.

Requirements

MD and board certification in Psychiatry or Neurology, with an active, unrestricted medical license.
Significant physician executive experience, typically 10 or more years post-residency, including 5 or more years in senior clinical leadership; ideally as CMO, Medical Director, or equivalent.
Demonstrated experience in digital health, health technology, or virtual care, including building or scaling a clinical function within a growth-stage technology company.
Strong technology mindset, hands-on experience partnering with product and engineering teams, and working understanding of AI/ML applications in healthcare.
Experience designing outcomes measurement and generating clinical and economic evidence that supports payer and enterprise adoption.
Working knowledge of digital health regulatory requirements, including FDA, HIPAA, CMS, and multi-state telehealth requirements.
Exceptional communication skills and executive presence, with credibility representing the company to payers, investors, partners, and the clinical community.
Based in, or willing to relocate to, the Boston area, with ability to work regularly in the office.

Nice To Haves

MBA or equivalent business training.
Certified Physician Executive or board certification in Medical Management or Addiction Medicine.
Experience in behavioral health, chronic pain, or musculoskeletal care delivered through technology-enabled models.
Experience leading clinical due diligence and integration in mergers and acquisitions.
Experience building and managing multi-state clinical provider networks.
Track record of peer-reviewed publications and speaking at major healthcare and digital health conferences.
Experience implementing clinical AI governance in a commercial healthcare setting.

Responsibilities

Define and execute clinical strategy across physical rehabilitation, chronic pain, and behavioral health, aligned with company growth and commercial priorities.
Lead, recruit, and develop the clinical organization, including clinical leadership, licensed providers, and clinical operations staff; build scalable clinical supervision and credentialing models.
Serve on the executive team and shape company strategy, product roadmap, and investment decisions from a clinical perspective.
Partner with the CTO and product teams to translate clinical evidence and behavioral science into product requirements, therapeutic content, and care pathways for the VR/AR platform.
Establish and own a clinical AI governance framework to ensure AI-driven features are clinically sound, safe, explainable, and compliant with privacy and regulatory requirements.
Provide clinical sign-off on product releases, protocols, and therapeutic programs.
Set the research and evidence agenda, including clinical studies, real-world evidence, peer-reviewed publications, and academic and industry partnerships.
Own outcomes measurement across clinical programs, defining clinical endpoints, engagement metrics, and patient-reported outcomes.
Develop health economic and ROI methodologies that meet the evidence requirements of payers, employers, and health system partners.
Own clinical quality, patient safety, and medical governance, including clinical policies, incident review, peer review, and continuous quality improvement.
Oversee clinical compliance with applicable federal and state requirements, including FDA, HIPAA, CMS, telehealth, multi-state licensure, and scope-of-practice rules, in partnership with Legal and Compliance.
Maintain clinical quality infrastructure that supports rapid product iteration without interrupting commercialization.
Represent XRHealth externally with payers, health plans, employers, health systems, regulators, media, and investors.
Support business development and payer contracting by presenting clinical value, outcomes data, and evidence in sales and partnership discussions.
Represent XRHealth at industry conferences and scientific and digital health forums.
Lead clinical due diligence on potential acquisitions and partnerships, and direct clinical integration of acquired programs, teams, and provider networks.