Biologist (3-5 years)

Real Soft•Boston, MA

About The Position

The Biologist will participate in the Gene Therapy in vivo pharmacology lab, executing experiments that support the discovery and optimization of novel therapeutic candidates for genetic medicines. The role works with team leads to design and conduct in vivo pharmacology experiments characterizing the activity, distribution, and clearance of genetic medicines in rodent models, and contributes to developing and characterizing novel in vivo models. The position collaborates with preclinical, toxicology, and PK/PD modelling partners to help translate discoveries into development.

Requirements

  • B.S. or M.S. in life sciences, such as biology or neuroscience, or 3–5 years of experience working in the pharmaceutical industry or a contract research organization.
  • Hands-on experience handling, dosing, and collecting blood from rodents, including mice and rats; techniques may include subcutaneous, intravenous, and intraperitoneal injections and submandibular, venipuncture, and cardiac puncture bleeds.
  • Ability to adapt and remain flexible as platform needs, workflows, and projects change.
  • Ability to craft, complete, and interpret experiments independently and advance scientific understanding.
  • Excellent communication skills and ability to collaborate across functional boundaries and in a team environment.
  • Strong organization skills, attention to detail, critical thinking, and ability to multitask.
  • Ability and desire to learn new techniques and contribute to innovative projects in a fast-paced working environment.
  • Experience processing, organizing, analyzing, and visualizing data and information from disparate sources, and extracting insight from data.

Nice To Haves

  • Experience with gross necropsies, tissue dissection, trimming, and processing.

Responsibilities

  • Work with team leads to design and execute in vivo pharmacology experiments characterizing the activity, distribution, and clearance of genetic medicines in rodent models, including mice, rats, and immuno-compromised animals.
  • Assist in the development and characterization of novel in vivo models.
  • Collaborate with cross-functional partners in preclinical, toxicology, and PK/PD modelling to support translation from discovery to development.
  • Provide written and verbal communication about work in study reports and team meetings.
  • Maintain accurate and timely documentation of practical work, including electronic notebooks aligned with Lilly procedure quality standards and Good Documentation Practices.
  • Ensure compliance with health and safety regulations.
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