TEMP - Associate Scientist, Translational Biology
About The Position
Employed through a preferred contingent supplier to support projects on-site or off-site for neurocrine. _ Your Contributions (include, but are not limited to): Independently execute in vivo PK/PD and/or efficacy studies that support nonclinical and clinical stage programs in the neurology and endocrinology disease space Administer small molecule compounds and biologics to naïve and disease-model rodents (mouse and rat), measure endpoints (body weight, clinical scores, behavioral) and collect biospecimens Follow study protocol, IACUC protocols, SOP and animal welfare policy in animal studies. Help maintain laboratory and supply inventories Have effective troubleshooting, problem-solving and communication skills Work both independently and collaboratively. Candidates must be flexible and have strong multitasking skills Collect, organize, and present scientific/technical data internally and in project team meetings Perform all duties in keeping with the Company’s core values, policies and all applicable regulations Performs assigned experiments to support scientific activities and project goals involving in vivo pharmacology assessment of novel therapeutics May design less complex experiments Recommends alternatives, researches new methods and techniques and may proactively seek out senior personnel to discuss potential solutions to problems Works with stereotaxic surgical techniques Oversees compound dosing via multiple routes of administration Responsible for behavioral assay development, validation and screening Completes data analysis and reporting. Maintains and updates SOP’s and writes data summaries for experiments conducted Handles and doses animals in a laboratory setting Reviews, comprehends and complies with all SOP’s, IACUC procedures, and safety and quality assurance standards at all times Provides training and/or supervision to junior staff, as needed Other duties as assigned
Requirements
- BS/BA degree in biological sciences preferably related to behavioral neuroscience, pharmacology or biopsychology and experience in the handling and dosing of rodents in a laboratory setting OR MS/MA degree in biological sciences preferably related to behavioral neuroscience, pharmacology or biopsychology and some relevant experience preferred
- Compound administration different routes (PO IP SC IM)
- Extensive hands-on knowledge of behavioral testing in a variety of assays like locomotor activity, fear conditioning
- Occasional weekend work required
- Recognizes fundamental anomalies in data points and identifies issues in experiments/processes
- Begins to understand how to think outside of the technical process and consider the impact decisions will have on the broader scientific goals
- Strong knowledge of one scientific discipline
- Good knowledge of scientific principles, methods and techniques
- Good knowledge and demonstrated ability working with a variety of laboratory equipment/tools
- Strong computer skills
- Good communications, problem-solving, analytical thinking skills
- Ability to meet deadlines
- Good project management skills
- High level of organization and attention to detail
- Willingness and ability to work both independently and as part of a team
- Must have working knowledge of Microsoft Office, Word, and Excel
- Advanced multitasking, trouble shooting and deductive reasoning skills required
Nice To Haves
- Previous experience with stereotaxic surgery, AAV administration and/or mouse colony maintenance and breeding is a plus
Responsibilities
- Independently execute in vivo PK/PD and/or efficacy studies that support nonclinical and clinical stage programs in the neurology and endocrinology disease space
- Administer small molecule compounds and biologics to naïve and disease-model rodents (mouse and rat), measure endpoints (body weight, clinical scores, behavioral) and collect biospecimens
- Follow study protocol, IACUC protocols, SOP and animal welfare policy in animal studies.
- Help maintain laboratory and supply inventories
- Have effective troubleshooting, problem-solving and communication skills
- Work both independently and collaboratively.
- Candidates must be flexible and have strong multitasking skills
- Collect, organize, and present scientific/technical data internally and in project team meetings
- Perform all duties in keeping with the Company’s core values, policies and all applicable regulations
- Performs assigned experiments to support scientific activities and project goals involving in vivo pharmacology assessment of novel therapeutics
- May design less complex experiments
- Recommends alternatives, researches new methods and techniques and may proactively seek out senior personnel to discuss potential solutions to problems
- Works with stereotaxic surgical techniques
- Oversees compound dosing via multiple routes of administration
- Responsible for behavioral assay development, validation and screening
- Completes data analysis and reporting.
- Maintains and updates SOP’s and writes data summaries for experiments conducted
- Handles and doses animals in a laboratory setting
- Reviews, comprehends and complies with all SOP’s, IACUC procedures, and safety and quality assurance standards at all times
- Provides training and/or supervision to junior staff, as needed
- Other duties as assigned
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What This Job Offers
Career Level
Entry Level
