Associate Scientist, Immunology
About The Position
AskBio Inc., a subsidiary of Bayer AG, is a gene therapy company focused on developing life-saving medicines. The company has a portfolio of clinical programs for various diseases and utilizes a proprietary cell line manufacturing process, Pro10™, along with an extensive array of capsids and promoters. With global headquarters in Research Triangle Park, North Carolina, and European headquarters in Edinburgh, Scotland, AskBio is dedicated to pioneering science to create transformative molecular medicines. The Associate Scientist, Clinical Immunology, will play a key role in understanding AAV Immunogenicity by performing immunological assays on clinical study samples to support gene therapy programs. This role involves leading assay development and validation, conducting real-time immune assessments of clinical studies, and supporting clinical sample coordination and management. It is an opportunity for a candidate with experience in Cell Biology and Immunology to advance gene therapy programs through clinical trial stages.
Requirements
- Bachelor’s degree in biology, chemistry, or related field and 8+ years’ relevant work experience; or Masters degree in biology, chemistry, or related field and 4+ years of relevant work experience
- Intermediate lab skills in cell biology, cell culture, immunology, reagent preparation, and adherence to biosafety and chemical use guidelines
- Familiarity with GCP/GLP/GxP lab standards and practices
- Familiarity with LIMS
- Basic office skills using a PC and working with MS office tools (Word, Excel and PowerPoint)
- Must be self-motivated, organized, capable of working independently as well as a team contributor
- Strong oral and written communication skills, particularly in writing technical documents such as SOPs, assay validation plans, reports and clinical sample testing plans and reports.
- Excellent interpersonal skills with the ability to interact effectively with teams, internally and externally
- Ability to work independently with minimal supervision under remote management as well as to work collaboratively with a broader team and across functional departments
Nice To Haves
- Experience in immunoassays such as ELISA, ELISPOT/FluoroSpot, neutralizing antibody, MSD, cytokine release and flow cytometry
- Previous experience working with human clinical samples, blood processing and downstream testing
- Experience with LabVantage LIMS
- Familiarity with statistical analysis
- Flexible schedule to accommodate real-time and urgent sample analysis
Responsibilities
- Perform complex assays without supervision
- Perform assay development of new clinical assays which may include the optimization, qualification, validation, and troubleshooting of new analytical methods
- Perform data analysis and interpret the results accurately
- Prepare validation reports and summaries
- Coordinate with Clinical team and/or Immunology lab manager for sample receiving and testing
- Support sample receiving and processing workflow
- Participate in team and clinical program meetings as needed to report results, discuss data and address program needs
- Build and maintain a compliant GxP lab environment and adhere to GLP/GcLP guidelines
- Author standard operating procedures (SOPs) for new assay protocols and use of new laboratory equipment
- Maintain a laboratory notebook or binder with worksheets recording details of performed experiments according to good documentation practices
- Train and mentor Research Associates and junior members of the laboratory
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
