Associate Scientist, Immunology

AskBio • Philadelphia, PA

4d • Onsite

About The Position

This role is a secondment opportunity at AskBio, available for a time period to be determined by leadership at both Bayer and AskBio, typically ranging from one to two years. This secondment offers a chance to broaden experience, expand knowledge, and contribute to AskBio’s mission of advancing gene therapy. The Associate Scientist, Clinical Immunology, is a key laboratory member contributing to the understanding of AAV Immunogenicity by performing analyses on clinical study samples using immunological assays in support of gene therapy programs. The role involves leading assay development and validation, performing real-time immune assessments of clinical studies, and supporting clinical sample coordination and management. This is an opportunity for a candidate looking to build upon experience in Cell Biology and Immunology lab skills in a scientific role focused on gene therapy advancement through clinical trial stages. The position reports to the Senior Director of Immunology.

Requirements

• Bachelor’s degree in biology, chemistry, or related field and 8+ years’ relevant work experience; or Masters degree in biology, chemistry, or related field and 4+ years of relevant work experience
• Intermediate lab skills in cell biology, cell culture, immunology, reagent preparation, and adherence to biosafety and chemical use guidelines
• Familiarity with GCP/GLP/GxP lab standards and practices
• Familiarity with LIMS
• Basic office skills using a PC and working with MS office tools (Word, Excel and PowerPoint)
• Must be self-motivated, organized, capable of working independently as well as a team contributor
• Strong oral and written communication skills, particularly in writing technical documents such as SOPs, assay validation plans, reports and clinical sample testing plans and reports.
• Excellent interpersonal skills with the ability to interact effectively with teams, internally and externally
• Ability to work independently with minimal supervision under remote management as well as to work collaboratively with a broader team and across functional departments

Nice To Haves

• Experience in immunoassays such as ELISA, ELISPOT/FluoroSpot, neutralizing antibody, MSD, cytokine release and flow cytometry
• Previous experience working with human clinical samples, blood processing and downstream testing
• Experience with LabVantage LIMS
• Familiarity with statistical analysis
• Flexible schedule to accommodate real-time and urgent sample analysis

Responsibilities

• Perform complex assays without supervision
• Perform assay development of new clinical assays which may include the optimization, qualification, validation, and troubleshooting of new analytical methods
• Perform data analysis and interpret the results accurately
• Prepare validation reports and summaries
• Coordinate with Clinical team and/or Immunology lab manager for sample receiving and testing
• Support sample receiving and processing workflow
• Participate in team and clinical program meetings as needed to report results, discuss data and address program needs
• Build and maintain a compliant GxP lab environment and adhere to GLP/GcLP guidelines
• Author standard operating procedures (SOPs) for new assay protocols and use of new laboratory equipment
• Maintain a laboratory notebook or binder with worksheets recording details of performed experiments according to good documentation practices
• Train and mentor Research Associates and junior members of the laboratory

Benefits

• Secondment opportunity

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level