Associate Scientist, HCP Analytics (Product Biochemistry)

Regeneron Pharmaceuticals•Tarrytown, GA

15d•$93,900 - $153,300•Onsite

About The Position

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Associate Scientist to join our Product Biochemistry group, supporting our Host Cell Protein (HCP) analytical program. In this role, you will focus on polyclonal antibody purification, ELISA method development, and related reagent generation activities that underpin our HCP impurity monitoring strategy across biologics programs. This position offers the opportunity to play a key role in enabling high-quality analytical support for process development, CMC, and regulatory filings, contributing to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

Requirements

BS/MS in Biochemistry, Chemistry, Molecular Biology, or a related life science discipline
Hands-on experience with protein purification (affinity chromatography, e.g., Protein A/G, antigen-affinity columns; AKTA or equivalent FPLC systems preferred)
Working knowledge of ELISA and general immunoassay techniques
Ability to work independently, manage multiple tasks in parallel, and maintain rigorous attention to detail
Excellent written and verbal communication skills; team-oriented mindset

Nice To Haves

Prior ELN experience
Strong documentation habits

Responsibilities

Purify polyclonal antibodies from rabbit/goat bleeds immunized with host cell protein antigens, using affinity chromatography and other standard purification workflows
Optimize and streamline purification protocols to improve yield, purity, reproducibility, and throughput
Support ELISA method development, qualification, and troubleshooting for HCP detection and quantitation
Prepare, aliquot, and manage critical reagents (antibodies, conjugates, standards, buffers) to ensure consistent assay performance
Document all experimental work in the electronic laboratory notebook (ELN) in accordance with defined procedures and departmental standards, and provide documentation upon request to support internal reviews, tech transfer, or regulatory submissions
Collaborate cross-functionally with process development, QC, and analytical teams to align on reagent needs and assay performance criteria
Contribute to continuous improvement of laboratory workflows and best practices