Scientist, Product Biochemistry

Regeneron Pharmaceuticals•Tarrytown, GA

2d•$93,900 - $153,300•Onsite

About The Position

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Scientist to join our Product Biochemistry team, on-site in Tarrytown, NY. In this role, you will support late-stage development (Phase II through commercialization) of biologics, developing and deploying analytical methods and purification strategies, enriching and characterizing product variants, and helping onboard new technologies that deepen product understanding and improve processes across the pipeline. This position offers the opportunity to bring scientific creativity, efficiency, and flexibility to a fast-paced, science-driven organization making a meaningful difference to patients worldwide.

Requirements

BS/MS in Biochemistry, Biophysics, Engineering, or a related field, with 8-10+ years of relevant industry experience
Strong lab skills in protein separation, purification, and tangential flow filtration (TFF), and skills in protein/product identification using mass spectrometry
Excellent oral and written communication skills and evidence of teamwork
Strong initiative to complete tasks, learn new technologies, and demonstrate a commitment to continuous learning
Ability to communicate clearly, transparently, and in a timely manner with key stakeholders

Nice To Haves

Technical proficiency in automated FPLC and/or HPLC (SEC, IEX, affinity), electrophoresis (capillary or microchip, SDS-PAGE, western blots), spectroscopy, and light scattering
Fundamental understanding of protein structure/function, mass spectrometry, and immunology/immunogenicity
Experience working in the biopharmaceutical industry

Responsibilities

Develop analytical methods and purification protocols to support extended characterization of therapeutic proteins and gene therapy vectors
Conduct biochemical/biophysical characterization to support development, regulatory submissions, and commercialization
Apply DOE, advanced statistics, and risk assessments to evaluate and optimize methods and processes
Design and execute experiments to enrich, purify, and characterize size/charge variants, complexes, and high-concentration formulations
Independently operate U/HPLCs and AKTA FPLCs, and perform capillary-based electrophoresis
Integrate learnings from internal data and external literature to make science-based study design recommendations
Author high-quality technical documents (protocols, reports, memos), contribute to regulatory sections and publications, and ensure timely documentation of experiments in accordance with established SOPs and guidelines
Document experiments, results, and findings in the electronic laboratory notebook, and present work at group and department meetings
Maintain instruments, troubleshoot instrumental/experimental problems, order/maintain supplies, and improve lab/data workflows within your area of expertise