Associate Scientist - David Solecki Lab (Chromatin Imaging in Neurons)

St. Jude Children's Research Hospital•Memphis, TN

9d•$65,520 - $114,400•Onsite

About The Position

The Associate Scientist performs a variety of moderately complex research tasks determined by the field and scope of the particular research project/study. Also, performs tasks related to the research project independently, but within broad guidelines and subject to periodic review by supervisor or other research staff. The Solecki Lab is building an imaging-based biosensor platform that makes chromatin states visible in living neurons and experimentally queryable as a cell-biological system. We are looking for an Associate Scientist who does not simply want to perform experiments but wants to help build the experimental framework for understanding how chromatin-state transitions unfold as neurons mature and assemble into brain circuits......by watching these processes happen in real time. Are you a researcher who wants to be scientifically invested in defining chromatin state beyond the limits of indirect molecular biology approaches? The successful candidate will independently take responsibility for platform areas like biosensor validation, chromatin live-cell imaging, neuronal differentiation assays, experimental perturbations, or analysis of complex time-sequence data. The position offers close collaboration with the PI and other team members to rapidly test emerging ideas in chromatin-state organization, neuronal maturation, and nuclear dynamics. Join a supportive multi-disciplinary lab comprised of biophysicists, optics experts, data scientists, cell-biologists and developmental neurobiologists that unravel how the brain is built during development. You will be on the ground floor of a transformative biosensor platform with exposure to cutting-edge imaging technologies like lattice light sheet or super-resolution platforms, data science core labs, and an unusually collaborative environment where new imaging probes, microscopy, and analytical methods converge on fundamental problems in brain development.

Requirements

PhD in cell biology, biophysics, gene regulation, neuroscience or related discipline.
Prior experience in live-cell imaging, super-resolution microscopy, and/or imaging probe development.
Familiarity with programming languages (e.g. R, Python) for data analysis.
Strong record of peer-reviewed publications.
Ability to independently design and execute experiments and interpret data.
Ability for cogent experimental preparation, validation, documentation, and troubleshooting.
Bachelor's degree in relevant scientific area is required.
7 + years of research experience is required.
5 + years of research experience is required with a Master’s degree.
2 + years of research experience is required with a PHD.

Nice To Haves

Experience leading and supporting research experiments preferred.
Some experience leading lab and scientific project coordination, maintenance, and other research support activities preferred.
Experience in guiding and training other laboratory personnel preferred.

Responsibilities

Independently take responsibility for platform areas like biosensor validation, chromatin live-cell imaging, neuronal differentiation assays, experimental perturbations, or analysis of complex time-sequence data.
Perform a variety of moderately complex research tasks determined by the field and scope of the particular research project/study.
Perform tasks related to the research project independently, but within broad guidelines and subject to periodic review by supervisor or other research staff.
Lead and support research experiments.
Coordinate, maintain, and provide other research support activities for scientific projects.
Guide and train other laboratory personnel.